Aminoglycosides and Glycopeptides Matthijs de Hoog John N. van den Anker Aminoglycosides General Aspects of Aminoglycosides Aminoglycosides have played a major role in antimicrobial therapy since their discovery in the…
Penicillins, Cephalosporins, and Other β-Lactams Sumathi Nambiar William J. Rodriguez The Penicillins Introduction Alexander Fleming discovered penicillin in 1928 (1). In the 1940s, penicillin became available for use in clinical…
Sulfonamides Chokechai Rongkavilit Nahed Abdel-Haq Jocelyn Y. Ang Basim I. Asmar Introduction Sulfonamides are some of the most common and the oldest antimicrobial agents used in children. Their mode of…
Ophthalmologic Drugs in Infants and Children John D. Roarty Introduction The study of ocular pharmacology in the pediatric population is often limited to case reports and small clinical series. This…
Topical Medications Victoria Tutag Lehr Mirjana Lulic Botica Merene Mathew Topical administration represents an important method of delivery of medications for infants and children. Clinicians must remember to inquire about…
Drug Therapy in the Adolescent Ian M. Paul Richard L. Levine Adolescence is a novel period in human development in which marked physical and physiologic changes occur. These are compounded…
Drug Therapy in the Pediatric Emergency Department* Shannon F. Manzi Michael W. Shannon Introduction Pharmacotherapy is an essential part of pediatric emergency medicine. Although few data are available, an estimated…
Therapeutic Applications in Pediatric Intensive Care Mary Lieh-Lai Ashok Sarnaik Introduction The worst thing about medicine is that one kind makes another necessary. –Elbert Hubbard Management of a critically ill…
Antiretroviral Pharmacology in Pregnant Women and Newborns Mark Mirochnick Brookie M. Best Introduction As infection with human immunodeficiency virus (HIV) continues to spread throughout the world, HIV/AIDS has become a…
Drugs and Perinatal Brain Injury Maria Delivoria-Papadopoulos Agustín Legido Ignacio Valencia Om Prakash Mishra Severe fetal asphyxia may have a broad range of effects on the brain from no evident…
