Section 4 Disruptions / Hypoxic-Ischemic Injury Cellular Responses Chapter 29 Neuronal Death Marc Del Bigio Neuron Death in the Developing Brain The idea that loss of neurons could be associated…

Neuroanatomic Site Development Chapter 19 Human Nervous System Development: Embryonic and Early Fetal Events Marc Del Bigio In human pregnancy, the developing individual is considered to be an embryo until…

Section 6 Perinatal Neurooncology Chapter 48 Congenital and Perinatal Brain Tumors Sanda Alexandrescu Introduction Central nervous system (CNS) tumors are the second most common neoplasms in the pediatric population, being…

Section 3 Stillbirth Autolysis, Artifacts, and Stillbirths Chapter 27 Autolysis and Artifacts Marc Del Bigio The word artifact is derived from the Latin words arte (“by skill”) and factum (“thing…

Prosection Techniques Chapter 9 Brain Prosection Marc Del Bigio Before the Autopsy The ability to conduct an autopsy safely and competently must be established. Guidelines for doing so have been…

Tissue Selection Chapter 13 Selection of Brain Areas for Microscopic Examination Mirna Lechpammer and Rebecca Folkerth Introduction Tissue specimens collected during the autopsy are largely used for diagnostic purposes; however,…

Approach to Autopsy of the Perinatal Nervous System Chapter 1 Clinical Considerations Rebecca Folkerth The initial steps in the process of perinatal nervous system evaluation, namely the planning of the…

Abstract Legal jurisdictions in most Western countries have legislation that allows acoroner or medical examiner to mandate an autopsy without consent by the next of kin in certain situations (e.g.,…