Glomerular Diseases   Allison A. Eddy   Glomerular diseases present clinically in several different ways, depending on the nature and severity of the primary disease and the extent to which…

Diabetes Mellitus   Arlan L. Rosenbloom   CLASSIFICATION AND DIAGNOSIS The diagnosis of diabetes includes a wide variety of diseases characterized by hyperglycemia. Because insulin is the only physiologically important…

Disorders of Digestion and Absorption   Ivor D. Hill and Ricardo A. Caicedo   EVALUATION OF THE CHILD WITH MALABSORPTION The assimilation of ingested nutrients involves a complex integrated process…

Arrhythmias   George F. Van Hare   GENERAL PRINCIPLES ANATOMY AND PHYSIOLOGY The heart has specialized cells collected into nodes and tracts. The sinoatrial node, near the junction of the…

Metabolic Abnormalities   William W. Hay Jr.   DISORDERS OF GLUCOSE METABOLISM Normal postnatal glucose homeostasis is established by increased glucose production and glucose utilization.1 Factors that promote glucose production…

Disorders of Glycogen Metabolism   Priya S. Kishnani and Yuan-Tsong Chen   GLYCOGEN STORAGE DISEASE Glycogen, the storage form of glucose in animal cells, is composed of glucose residues joined…

Anemia Due to Diminished Red Blood Cell Production   Zora R. Rogers   Anemia may be the first recognized hematologic finding in a child whose bone marrow is not functioning…