JUVENILE RHEUMATOID ARTHRITIS Print Section Listen Juvenile rheumatoid arthritis (JRA) is a generalized systemic disease of unknown etiology characterized by a transient macular, papular, or urticarial rash and ensuing fever,…

PSORIASIS Print Section Listen Psoriasis is a hereditary disorder of skin characterized by chronic scaling papules and plaques in a characteristic distribution, largely at sites of repeated minor trauma. The…

INTRODUCTION Print Section Listen Skin color is genetically determined and is caused by the total amount of melanin pigment in the skin. Normal constitutive melanin pigmentation determines skin type, which…

CONGENITAL VASCULAR LESIONS Print Section Listen INSIGHT It is important to differentiate between the three most common vascular anomalies in newborns: capillary stains that self-resolve, port-wine stains that benefit from…

HISTIOCYTOSIS Print Section Listen The disorders of xanthohistiocytic proliferation involving histiocytes, foam cells, and mixed inflammatory cells are divided into Langerhans cell histiocytosis (LCH) and non-Langerhans cell histiocytosis (non-LCH). LANGERHANS…

ACANTHOSIS NIGRICANS Print Section Listen Acanthosis nigricans (AN) is a diffuse, velvety thickening and hyperpigmentation of the skin, chiefly in axillae and other body folds, which may be related to…

PAPULOSQUAMOUS ERUPTIONS Print Section Listen PITYRIASIS ROSEA Pityriasis rosea (PR) is a common, benign, self-limited whole body rash with a seasonal prevalence that is clinically characterized by a solitary “herald…

INTRODUCTION Print Section Listen The neurocutaneous disorders are a group of inherited conditions associated with skin, peripheral and central nervous system (CNS), and other systemic abnormalities. Embryologically, the skin and…

CONNECTIVE TISSUE NEVUS Print Section Listen Connective tissue nevi are benign, slightly elevated, well-circumscribed plaques that are often seen as an isolated skin finding, but can also be associated with…

ACQUIRED MELANOCYTIC NEVI Print Section Listen Acquired melanocytic nevocellular nevi are small (<1 cm), benign, well-circumscribed, pigmented lesions comprised of groups of melanocytes or melanocytic nevus cells. They can be…