Objectives The antibody immunoglobulin D (IgD) is evolutionarily conserved throughout the 500 million years of vertebrate evolution1, but its function has long been mysterious since its discovery over 50 years…
Objectives Our objective was to evaluate HIV RNA virologic suppression and pregnancy outcomes for women with perinatally acquired HIV infection (PHIV) compared to women with non-perinatal HIV (nPHIV) infection over…
Objectives The 2015 Zika virus (ZIKV) outbreak and the fear associated with the risk of microcephaly led to an influx of potentially exposed pregnant women into the health care system,…
Objectives The clinical diagnosis of chorioamnionitis requires a high index of suspicion. Unrecognized and untreated chorioamnionitis can lead to poor maternal and neonatal outcomes. Recent study of the concordance between…
Objectives To evaluate the negative predictive value (NPV) of a rapid influenza diagnostic test (RIDT) in comparison with that of a real-time reverse transcription (rRT)-PCR test in pregnant women. Methods…
Objectives NDV3A-003 evaluated the safety, immunogenicity and efficacy of a vaccine, NDV-3A, to reduce the frequency and severity of infections in women with recurrent vulvovaginal candidiasis (RVVC). Methods NDV-3A is…
Objectives SYM-1219, a granule formulation of secnidazole, is being developed as a single oral dose therapy for bacterial vaginosis (BV). A previous study of SYM-1219 for the treatment of BV…
Objectives To evaluate the efficacy and safety of VT-1161, a potent, highly selective inhibitor of fungal CYP51, in treating women with a documented history of recurrent vulvovaginal candidiasis (RVVC). Methods…
Objectives Maternal sepsis is associated with high maternal morbidity and mortality. However, neonatal outcomes after maternal sepsis during pregnancy have not been described. The goal of this study was to…
Objectives Sepsis can develop in the peripartum period and increase the risk of maternal morbidity and mortality. The objective of this study is to determine if obstetrical complications are associated…
