Objective To evaluate PIK3CA mutational status and c-erbB2 gene amplification in a series of primary uterine serous carcinomas (USC) cell lines. To assess the efficacy of GDC-0980, a potent inhibitor…
Objective The purpose of this study was to describe patient preferences for uterine preservation and hysterectomy in women with pelvic organ prolapse symptoms and to describe predictors of preference for…
Objective The goal of the study was to examine risks in pregnancy in patients with Ebstein anomaly. Study Design Data were examined retrospectively for 13 patients (27 pregnancies, 21 live…
Objective Regulatory bodies and insurers evaluate hospital quality using obstetrical outcomes, however meaningful comparisons should take preexisting patient characteristics into account. Furthermore, if risk-adjusted outcomes are consistent within a hospital, fewer…
Objective The purpose of this study was to examine the risks of acute coronary syndrome (ACS) and acute myocardial infarction (AMI) that are associated with methylergonovine maleate (Methergine; Novartis Pharmaceuticals…
Objective Hyperhomocysteinemia is associated with an elevated cardiovascular disease risk. We examined whether women with a history of hypertension in pregnancy are more likely to have a high level of…
Objective Preterm birth at very low birthweight (<1500 g) is associated with cardiometabolic risk factors and reduced bone mineral density in the adult offspring. Preeclampsia is a frequent cause of…
Objective Because the diagnosis of postpartum hemorrhage (PPH) depends on the accoucheur’s subjective estimate of blood loss and varies according to mode of delivery, we examined temporal trends in severe…
Objective We sought to evaluate population gestational diabetes mellitus (GDM) screening results and risk for incident insulin treatment. Study Design Among 64,687 pregnant women universally screened for GDM from 1995…
Objective The purpose of this study was to estimate the usefulness of the fetal-pelvic index (FPI) in the prediction of cesarean delivery among nulliparous and women who undergo a trial…
