GYNECOLOGY

Long-term health outcomes of children born to mothers with hyperemesis gravidarum: a systematic review and meta-analysis

Aug 28, 2022 by in GYNECOLOGY Comments Off on Long-term health outcomes of children born to mothers with hyperemesis gravidarum: a systematic review and meta-analysis

Objective Hyperemesis gravidarum is characterized by severe nausea and vomiting in pregnancy, frequently resulting in severe maternal nutritional deficiency. Maternal undernutrition is associated with adverse offspring health outcomes. Whether hyperemesis…

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Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A comprehensive and systematic review with meta-analysis

Aug 28, 2022 by in GYNECOLOGY Comments Off on Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A comprehensive and systematic review with meta-analysis

Objective This study aimed to present a narrative review regarding androgen production, androgens’ role in folliculogenesis, and the available therapeutic approaches for androgen supplementation, and to perform a systematic review…

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Maternal obesity during pregnancy leads to derangements in one-carbon metabolism and the gut microbiota: implications for fetal development and offspring wellbeing

Aug 28, 2022 by in GYNECOLOGY Comments Off on Maternal obesity during pregnancy leads to derangements in one-carbon metabolism and the gut microbiota: implications for fetal development and offspring wellbeing

A healthy diet before and during pregnancy is beneficial in acquiring essential B vitamins involved in 1-carbon metabolism, and in maintaining a healthy gut microbiota. Each play important roles in…

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Recurrent bacterial vaginosis following metronidazole treatment is associated with microbiota richness at diagnosis

Apr 16, 2022 by in GYNECOLOGY Comments Off on Recurrent bacterial vaginosis following metronidazole treatment is associated with microbiota richness at diagnosis

Background Bacterial vaginosis—a condition defined by a shift from Lactobacillus dominance to a polymicrobial, anaerobic bacterial community—increases the risk of acquiring sexually transmitted infections and other complications of the female…

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The selective progesterone receptor modulator-promegestone-delays term parturition and prevents systemic inflammation-mediated preterm birth in mice

Apr 16, 2022 by in GYNECOLOGY Comments Off on The selective progesterone receptor modulator-promegestone-delays term parturition and prevents systemic inflammation-mediated preterm birth in mice

Background Progesterone, acting via its nuclear receptors called progesterone receptors, promotes myometrial relaxation during pregnancy, and suspension of this activity triggers labor. We previously found that 20α-hydroxysteroid dehydrogenase causes a…

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