GYNECOLOGY

General maternal medication use, folic acid, the MDR1C3435T polymorphism, and the risk of a child with a congenital heart defect

Jun 21, 2017 by in GYNECOLOGY Comments Off on General maternal medication use, folic acid, the MDR1C3435T polymorphism, and the risk of a child with a congenital heart defect

Objective We sought to investigate maternal and child functional MDR1 C3435T polymorphism, periconception medication, folic acid use, and the risk of a congenital heart defect (CHD) in the offspring. Study…

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Routine use of abdominopelvic ultrasonography in severe postpartum hemorrhage: retrospective evaluation in 125 patients

Jun 21, 2017 by in GYNECOLOGY Comments Off on Routine use of abdominopelvic ultrasonography in severe postpartum hemorrhage: retrospective evaluation in 125 patients

Objective The purpose of this study was to analyze the potential of abdominopelvic ultrasonography at the initial examination in women with severe postpartum hemorrhage. Study Design One hundred twenty-five women…

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Familial aggregation of hyperemesis gravidarum

Jun 21, 2017 by in GYNECOLOGY Comments Off on Familial aggregation of hyperemesis gravidarum

Objective This study was undertaken to determine whether there is familial aggregation of hyperemesis gravidarum (HG), making it a disease amenable to genetic study. Study Design Cases with severe nausea…

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Protein kinase Cβ2 inhibition reduces hyperglycemia-induced neural tube defects through suppression of a caspase 8-triggered apoptotic pathway

Jun 21, 2017 by in GYNECOLOGY Comments Off on Protein kinase Cβ2 inhibition reduces hyperglycemia-induced neural tube defects through suppression of a caspase 8-triggered apoptotic pathway

Objective Neural tube defects in diabetic embryopathy are associated with increased protein kinase C (PKC)β2 activity and programmed cell death (apoptosis). The apoptosis is triggered by caspase 8, which activates…

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17-hydroxyprogesterone caproate for twin pregnancy: a double-blind, randomized clinical trial

Jun 21, 2017 by in GYNECOLOGY Comments Off on 17-hydroxyprogesterone caproate for twin pregnancy: a double-blind, randomized clinical trial

Objective We sought to determine whether prophylactic treatment with 17-alpha-hydroxyprogesterone caproate (17Pc) in twin pregnancy will reduce neonatal morbidity (primary outcome) by prolonging pregnancy (secondary outcome). Study Design This was…

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Use of the Learning Curve–Cumulative Summation test for quantitative and individualized assessment of competency of a surgical procedure in obstetrics and gynecology: fetoscopic laser ablation as a model

Jun 21, 2017 by in GYNECOLOGY Comments Off on Use of the Learning Curve–Cumulative Summation test for quantitative and individualized assessment of competency of a surgical procedure in obstetrics and gynecology: fetoscopic laser ablation as a model

Objective We sought to determine the learning curve (LC) for fetoscopic laser photocoagulation (FLP) as a model for the evaluation of training in surgical procedures. Study Design A retrospective review…

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