Pediatric Orthopedics for the Primary Care Provider
P. Christopher Cook, MD, FRCS(C), Editor It has been a great pleasure to help compile this Pediatric Orthopedic issue of the Pediatric Clinics of North America . Pediatric orthopedics has…
Pediatric Orthopedics
Bonita F. Stanton, MD, Consulting Editor Among the many important decisions that general pediatricians must make on a daily basis are those depending on the recognition of conditions requiring timely…
Remaining Challenges in Childhood Cancer and Newer Targeted Therapeutics
Despite the enormously important and gratifying advances in cancer treatment outcomes for children with cancer, cancer remains the biggest cause of death from disease in children. Because the etiology and…
Late Effects of Childhood Cancer and Its Treatment
Treatment for childhood cancer with chemotherapy, radiation and/or hematopoietic cell transplant can result in adverse sequelae that may not become evident for many years. A clear understanding of the association…
Hematopoietic Cell Transplantation and Cellular Therapeutics in the Treatment of Childhood Malignancies
Hematopoietic cell transplantation (HCT) represents the most common and effective form of immunotherapy for childhood malignancies. The role of the graft-versus-leukemia effect in allogeneic HCT has been well established in…
Neuroblastoma
Neuroblastoma (NB) is the third most common pediatric cancer. Although NB accounts for 7% of pediatric malignancies, it is responsible for more than 10% of childhood cancer-related mortality. Prognosis and…
Retinoblastoma
Retinoblastoma is the most common neoplasm of the eye in childhood, and represents 3% of all childhood malignancies. Retinoblastoma is a cancer of the very young; two-thirds are diagnosed before…
Brain Tumors
The past 2 decades have witnessed a revolution in the management of childhood brain tumors, with the establishment of multidisciplinary teams and national and international consortiums that led to significant…
Pediatric Lymphomas and Histiocytic Disorders of Childhood
Although there have been dramatic improvements in the treatment of children with non-hodgkin lymphoma, hodgkin lymphoma and histiocytic disorders over the past 3 decades, many still relapse or are refractory…
