Antenatal fetal surveillance in multiple pregnancies
Multiple pregnancies occur either spontaneously or because of assisted reproduction techniques in 1–3% of pregnancies. The presence of more than one fetus in the womb is associated with a range…
Role of uteroplacental and fetal Doppler in identifying fetal growth restriction at term
Identification of the fetus at risk of adverse outcome at term is a challenge to both clinicians and researchers alike. Despite the fact that fetal growth restriction (FGR) is a…
Early onset fetal growth restriction
Fetal growth restriction remains a challenging entity with significant variations in clinical practice around the world. The different etiopathogenesis of early and late fetal growth restriction with their distinct progression…
Antenatal fetal surveillance “Assessment of the AFV”
The evaluation of amniotic fluid volume (AFV) is an established part of the antenatal surveillance of pregnancies at risk for an adverse pregnancy outcome. The two most commonly used ultrasound…
Antenatal foetal heart monitoring
Antenatal foetal heart rate assessment was introduced into clinical medicine before clear evidence of any benefits had been reported. Ad hoc definitions were used to define normal and abnormal recordings…
Thalassaemia in Obstetric Practice – Multiple Choice Questions for Vol. 39
1. Plausible explanations for the detection of false positive results in NIPT of fetal aneuploidies are which of the following? a) Low fetal DNA fractions b) Confined placental mosaicism c)…
Antenatal Fetal Surveillance – Multiple Choice Answers for Vol. 39
1. The gold standard test for antenatal surveillance of the pregnancy at-risk for an adverse pregnancy outcome with the lowest false negative rate is: a) Biophysical Profile b) CTG only…
Obstetric care for women with thalassemia
Thalassemia is the commonest monogenic disease and manifests as severe anemia. It is increasingly encountered outside the Mediterranean region, Africa, Middle East, and Southeast Asia because of immigration. Pregnancy, previously…
Non-invasive prenatal diagnosis of thalassemias using maternal plasma cell free DNA
Non-invasive prenatal testing (NIPT) using maternal plasma cell free DNA has already reshaped the existing prenatal care system for pregnancies screened for common chromosomal aneuploidies. On the other hand, much…
Pre-implantation genetic diagnosis
The aim of pre-implantation genetic diagnosis (PGD) is to characterize the genetic status of the cells (usually single cells) that have been biopsied from oocytes/zygotes or embryos created in vitro during…
