Malignant ovarian germ-cell tumours

Nov 9, 2017 by in OBSTETRICS Comments Off on Malignant ovarian germ-cell tumours

Malignant ovarian germ-cell tumours account for about 5% of all ovarian malignancies and typically present in the teenage years. They are almost always unilateral and are exquisitely chemosensitive. As such,…

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Epithelial ovarian cancer

Nov 9, 2017 by in OBSTETRICS Comments Off on Epithelial ovarian cancer

The incidence of epithelial ovarian cancer in women aged 40 years and younger is 3–17%. The management of these women is challenging and requires balancing the need to treat epithelial…

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Borderline ovarian tumours

Nov 9, 2017 by in OBSTETRICS Comments Off on Borderline ovarian tumours

Borderline ovarian tumours account for 10–20% of all epithelial ovarian cancer. Historically, standard primary surgery has included borderline ovarian tumours, omentectomy, peritoneal washing and multiple biopsies. As one-third of borderline…

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Endometrial cancer

Nov 9, 2017 by in OBSTETRICS Comments Off on Endometrial cancer

Endometrial carcinoma is the most common gynaecological malignancy in the Western world. The standard management of endometrial carcinoma is total hysterectomy and bilateral salpingo-oophorectomy with or without pelvic and para-aortic…

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Cervical cancer

Nov 9, 2017 by in OBSTETRICS Comments Off on Cervical cancer

Standard treatment for invasive cervical cancer involves either radical surgery or radiotherapy. Childbearing is therefore impossible after either of these treatments. A fertility-sparing option, however, by radical trachelectomy has been…

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Vaginal microbicides to prevent human immunodeficiency virus infection in women: Perspectives on the female genital tract, sexual maturity and mucosal inflammation

Nov 9, 2017 by in OBSTETRICS Comments Off on Vaginal microbicides to prevent human immunodeficiency virus infection in women: Perspectives on the female genital tract, sexual maturity and mucosal inflammation

Topically applied vaginal microbicides to protect against human immunodeficiency (HIV) virus infection offer an important female-controlled prevention strategy. Microbicides have been in development for more than 2 decades, and have…

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Future strategies in microbicide development

Nov 9, 2017 by in OBSTETRICS Comments Off on Future strategies in microbicide development

The reduction in human immunodeficiency virus (HIV) infection in women demonstrated by pericoital use of tenofovir gel has encouraged the continued development of microbicides. Novel approaches include new ways to…

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