Latex Allergy
Key Points • Natural rubber latex (NRL) is contained in thousands of consumer and medical products and is responsible for an epidemic of IgE-mediated latex allergy in the past three…
Urticaria and Angioedema
Key Points • The distinction between acute and chronic urticaria/angioedema has important diagnostic and therapeutic implications. Recurrent angioedema without urticaria suggests the possibility of hereditary angioedema. • The most common…
Drug Allergy
Key Points • While true drug hypersensitivity is relatively uncommon, many children are labeled as being ‘allergic’ to various medications, particularly antibiotics. They end up carrying this label into adulthood…
Role of Barrier Dysfunction and Immune Response in Atopic Dermatitis
Key Points • Pruritus and chronic or relapsing eczematous dermatitis with typical distribution are essential for diagnosis of atopic dermatitis (AD). • Interactions between susceptibility genes, the host’s environment, pharmacologic…
Contact Dermatitis
Key Points • Allergic contact dermatitis (ACD) in children is not uncommon and should be suspected in patients with chronic dermatitis. • Patch testing is the gold standard for the…
Management of Atopic Dermatitis
Key Points • Proper skin hydration and skin barrier protection are key to management of atopic dermatitis (AD). • Topical antiinflammatory therapy includes use of topical steroids and calcineurin inhibitors….
Immunotherapeutic Approaches to the Treatment of Food Allergy
Key Points • Restoration or induction of immune tolerance is the primary goal for immunotherapy (IT) for food allergy, requiring significant immunomodulation to be effective. • Emerging immunotherapeutic approaches to…
Atopic Dermatitis and Food Hypersensitivity
Key Points • About one third of children with moderate to severe atopic dermatitis (AD) are affected by food hypersensitivity. • A food allergy evaluation should be considered in children…
Management of Food Allergy
Key Points • The management of food allergy entails dietary avoidance of the identified allergen to prevent chronic and acute food allergic reactions. • Allergen elimination diets should not be…
Oral Allergy Syndrome
Key Points • OAS is an IgE-mediated allergy that is due to cross-reactivity between pollens and homologous food proteins. • There is significant regional variation in OAS prevalence. • Several…
