Chapter Outline Introduction and Terminology 349 Two Diseases 350 The Spectrum of Non-Atypical Endometrial Hyperplasias 350 Disordered Proliferative Endometrium: a Prelude to Non-Atypical Hyperplasia 352 Non-Atypical Hyperplasia 353 Non-Atypical Hyperplasia…
Chapter Outline Introduction 828 Broad Spectrum Differentiation Markers 828 Epithelial Markers 828 Mesenchymal Cell Markers 831 Smooth Muscle Markers 831 Skeletal Muscle Markers 832 Endometrial Stromal Markers 832 Mesothelial Markers…
George L. Mutter Jaime Prat The purpose of tumor staging is two-fold: to provide standardized terminology that allows comparison of patients between centers; and to distribute patients and their tumors into prognostic…
Chapter Outline Epithelial Tumors 275 Adenoid Basal Carcinoma (Adenoid Basal Epithelioma) 275 Adenoid Cystic Carcinoma 277 Neuroendocrine Tumors 277 Typical (Classic) Carcinoid Tumor 277 Atypical Carcinoid Tumor 277 Small Cell…
Chapter Outline Tumor-Like Conditions 116 Fibroepithelial–Stromal Polyp (Pseudosarcoma Botryoides) 116 Nodular Fasciitis 117 Benign Neoplasms 118 Angiomyofibroblastoma 118 Cellular Angiofibroma 119 Prepubertal Vulvar Fibroma 120 Dermatofibroma (Fibrous Histiocytoma) 121 Granular…
Chapter Outline Introduction 310 Estrogens 310 Progestins 312 Oral Contraceptives 313 Combined OCs 314 Pure Progestin OCs (‘Mini-pill’) 315 Long-term, Progestin-only OCs 315 Hormone Replacement Therapy 315 Unopposed Estrogen HRT…
Chapter Outline Epidemiology and Staging 232 Types of Cervical Malignancies 233 Superficially Invasive Squamous Cell Carcinoma 233 Depth of Invasion 234 Morphologic Features 235 Squamous Cell Carcinoma 238 Microscopic Features…
Chapter Outline Cysts 95 Follicular (‘Epidermoid’) Cyst 95 Steatocystoma Multiplex 96 Bartholin Cyst 96 Mucinous Cyst 97 Ciliated Cyst (Paramesonephric Cyst) 97 Paraurethral (Skene) Gland Cyst 97 Mesonephric-Like Cyst 97…
Chapter Outline Introduction 188 HPV Infection 188 Low-Grade Squamous Intraepithelial Lesions (CIN1) 191 High-Grade Squamous Intraepithelial Lesions (CIN 2/3) 191 Mechanisms of Oncogenesis 192 The HPV E6 and E7 Oncoproteins…
Chapter Outline Benign Squamous Neoplasms 79 Condyloma Acuminatum 79 Seborrheic Keratosis 79 Keratoacanthoma 80 Squamous Intraepithelial Lesions of the Vulva (VIN) 81 HPV-related Low- and High-grade Squamous Intraepithelial Lesions (VIN…
