Acknowledgments This work was supported by Grants PI1501686, PIE1600050, and PI1801122 from Instituto de Salud Carlos III, Spanish Ministry of Economy and Competitiveness, and co-financed by the European Development Regional…
Acknowledgments This chapter is dedicated to Prof. Renato Pasquali, for his constant commitment to the study of PCOS. Introduction PCOS has had a complex history punctuated by a constant improvement…
Eva Pajkrt and Liesbeth van Leeuwen Dilatation and evacuation Worldwide, together with aspiration, dilatation and evacuation (D&E) is still the most frequently used method of termination of pregnancy. There is…
Karin E.M. Diderich Diagnosis, counseling, and decision-making This is the timeframe during which couples hear the (most likely) diagnosis and have to make the decision to terminate or continue the…
Both Lara and Iris are Dutch. In the Netherlands, couples are legally allowed to terminate a pregnancy for fetal congenital abnormalities up to 24 weeks of pregnancy. Lara : Mae…
Introduction Because of their welfare and relatively economic and political stability, the postindustrial countries in the world are preferred by immigrants, which results in the increasing diversity of the population…
What is uncertain in prenatal genomics? Most prospective parents enter into the screening and diagnostic process with the assumption that the information they receive will be clear-cut and straightforward. In…
Denmark was one of the first countries in the world to introduce a universal and free-of-charge offer of combined first-trimester screening (CFTS) for chromosomal anomalies to all pregnant women. In…
Introduction The introduction of whole-exome sequencing (WES) in prenatal diagnostics results in an increase in resolution and diagnostic yield. This is, however, not the first time a new technique changes…
