First Trimester Pregnancy Complication
First Trimester Pregnancy Complication 5.1 Early Pregnancy Failure Description and Clinical Features The rate of pregnancy loss is highest in the first trimester, especially before 8 weeks gestation. A number…
Fetal Anomalies at 11–14 Weeks
Fetal Anomalies at 11–14 Weeks 4.1 Thickened Nuchal Translucency Description and Clinical Features The thickness of the tissue posterior to the cervical spine at 10–14 weeks, called the nuchal translucency,…
Second and Third Trimester Fetal Anatomy
Second and Third Trimester Fetal Anatomy 2.1 Head Description and Clinical Features By the beginning of the second trimester, the fetal cranium and brain are well formed, although the skull…
First Trimester
First Trimester 1.1 Normal Pregnancy Prior to 6 Weeks of Gestation Description and Clinical Features Fertilization occurs at approximately 14 days after the beginning of the last menstrual period (LMP)….
Second and Third Trimester Nonfetal Components
Second and Third Trimester Nonfetal Components 3.1 Umbilical Cord Description and Clinical Features The umbilical cord contains the blood vessels that carry blood between the fetus and the placenta. It…
Preimplantation Genetic Testing
Abbreviations aCGH Array comparative genomic hybridization AF Amniotic fluid CRISPR Clustered regularly interspaced short palindromic repeat CVS Chorionic villus sampling FISH Fluorescence in situ hybridization HDR Homology directed repair ICM…
Fetal Treatment of Genetic Disorders
In Utero Stem Cell Transplantation In utero hematopoietic stem cell transplantation (IUHCT) is a promising approach to treat congenital genetic disorders. IUHCT offers multiple therapeutic advantages over postnatal bone marrow…