Overview of metabolic risk profile and complications of NAFLD Excessive hepatic fat accumulation defines the primary event in the continuum of nonalcoholic fatty liver disease (NAFLD) that has become the…
Introduction Polycystic ovary syndrome (PCOS) is associated with neuroendocrine dysfunctions, insulin resistance (IR), impaired ovarian steroidogenesis and hyperandrogenism . Although the etiology of PCOS is still poorly known, androgens and…
Introduction The myth of Ariadne’s thread is a fitting analogy for providing a practical and logical algorithm for the management of anovulatory PCOS. The legend tells of King Minos who,…
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among reproductive-aged women characterized by clinical or biochemical hyperandrogenism, oligo-anovulation, and polycystic ovarian morphology. Women with PCOS have increased risk…
Introduction Polycystic ovary syndrome (PCOS), a multifactorial disorder, involves mainly reproductive but also other endocrine systems. Based on the current Rotterdam criteria, the prevalence of PCOS varies between 5% and…
Funding sources This work was supported by the Brazilian National Institute of Hormones and Women’s Health/Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq INCT grant number 465482/2014-7) and Fundação de…
Obesity, insulin resistance and metabolic syndrome in PCOS Overweight and obesity constitute a modern global pandemic, with rapidly growing rates both in developed and in developing areas of the world….
Funding This work was supported by academic grants to Paolo Moghetti from the University of Verona. Conflicts of interest/competing interests The author has nothing to disclose. Introduction Polycystic ovary syndrome…
Introduction Polycystic ovary syndrome (PCOS) is a very common and rather complex endocrine disorder with significant reproductive and metabolic impact . The overproduction of androgens seems to have a role…
Acknowledgments Financial Support: D.H.A. and J.E.L.: NIH DK121559, HD102172, OD011106. Introduction Polycystic ovary syndrome (PCOS) is a prevalent, complex, highly heritable, subfertility health disorder of premenopausal women with numerous comorbidities…
