Abstract Obstructive azoospermia (OA) is a common presenting condition of male infertility, resulting from either congenital or acquired blockage of the reproductive tract. Men facing a diagnosis of OA now…
Abstract This chapter is a narrative review of the epidemiology of IVF and ICSI as the dominant sub-set of all available assisted reproductive technologies (ART). Chapter 12 Perinatal Outcomes from…
Abstract While intracytoplasmic sperm injection (ICSI) is the most significant advance in assisted reproductive technology (ART) for the alleviation of male factor subfertility, its use has become increasingly widespread and…
Abstract Up to the 1980s the ability to treat couples with male subfertility was limited. Treatable conditions included gonadotrophin therapy for men with hypogonadotrophic hypogonadism (which is estimated to be…
Abstract Infertility is defined as a failure of spontaneous conception after one year of regular sexual intercourse in the absence of contraceptive measures [1]. This entity represents a rising medical…
Abstract The regulation of the endocrine and reproductive function of the testis is under the concerted action of gonadotropin-releasing hormone (GnRH) and gonadotropins, such as luteinizing hormone (LH) and follicle-stimulating…
Abstract The primary aim of this chapter is to provide practical, evidence-based information pertinent to the specific detection of anti-sperm antibodies (ASA) in males and females and the assessment of…
Abstract This chapter provides detailed practical information about testing for sperm antibodies and interpretation of the results of various antibody tests. It also briefly reviews our knowledge about anti-sperm antibodies…
Abstract This chapter considers the effect of paternal age on semen analysis, sperm function and DNA damage, as well as age-related impact on male fertility, both natural conception (time to…
Abstract The sperm epigenome is unique and of profound clinical importance based on its role in influencing embryogenesis. Potentially, the sperm epigenome can also be of importance to the clinician…
