Fig. 5.1 Molecular structure of bisphosphonates. The generic bisphosphonate structure (left) with two phosphonate groups binding to a central carbon atom. Modern bisphosphonates have a hydroxyl group and specific nitrogen-containing…
Fig. 10.1 Molecular structure of D2 and D3 Table 10.1 Food sources of vitamin D and calcium Dietary sources of calcium and vitamin D Calcium content Vitamin D content Breast…
Gordon L. Klein (ed.)Bone Drugs in Pediatrics2014Efficacy and Challenges10.1007/978-1-4899-7436-5_13 © Springer Science+Business Media New York 2014 13. Conclusion: Whither (or Wither?) the Pharmacology of Pediatric Bone? Gordon L. Klein1 (1) Department Orthopaedic Surgery and Rehabilitation, University…
Fig. 3.1 Current model of osteoblast differentiation from stem cell. Ihh is the initiator of endochondral ossification. The Runx2-expressing bipotential progenitors can differentiate into either osteoblast or chondrocyte. Then cells…
Fig. 9.1 This figure illustrates the interlinking cascade of the growth hormone system throughout the body. GH growth hormone, GHBP GH binding protein, GH-S GH secretagogues, IGF-1 insulin-like growth factor-1,…
Gordon L. Klein (ed.)Bone Drugs in Pediatrics2014Efficacy and Challenges10.1007/978-1-4899-7436-5_1 © Springer Science+Business Media New York 2014 1. Introduction Gordon L. Klein1 (1) Department of Orthopaedic Surgery and Rehabilitation, University of Texas Medical Branch and Shriners Burns…
Patient age Total body watera Extracellular fluida Intracellular fluida <3-Month fetus 92 65 25 Term gestation 75 35–44 33 4–6 months 60 23 37 12 months 26–30 Puberty ~60 20…
Diagram 21.1 Fertilization of an empty ovum by sperm containing 23X haploid set of chromosome which duplicates to form 46XX Paternal Origin of Partial Hydatidiform Mole Partial hydatidiform moles are…
Fig. 13.1 Correlation of T3, T4 and TSH values with thyroid disorders observed during screening Fig. 13.2 Changes in maternal and foetal thyroid function during pregnancy Interestingly, the secretion of…
Fig. 37.1 Insertion of the membrane on the placenta – “T” sign indicated monochorionicity and “λ” sign indicated dichorionicity Dichorionic diamniotic (DCDA) twins form when splitting takes place by the…
