High risk Cyclophosphamide Ifosfamide Melphalan Busulfan Intermediate risk Cisplatin with low cumulative dose Carboplatin with low cumulative dose Adriamycin Low risk Actinomycin D Vincristine Methotrexate 5.3 Female Fertility Female fertility…
Reference Response grade Response grade definition Huvos (1988), Provisor et al. (1997) I Viable; little to no chemotherapeutic effect II Partially necrotic III Largely necrotic IV Totally necrotic; no histologic…
Group Era n Dose (Gy) 5-year overall LC (%) LC with RT alone IESS-I 1973–1978 331 45–65 85 IESS-II 1978–1982 214 50–55 90 SJCRH 1978–1988 43 30–60 68 58 CESS-81…
Fig. 1.1 Location of primary tumors in osteosarcoma and Ewing sarcoma (percentage) Fig. 1.2 Presenting symptoms in osteosarcoma and Ewing sarcoma (percentage) 1.3 Sex and Ethnicity There is a slight…
Fig. 2.1 Hypothetical model of the process of adaptation, from initial coping to adherence Stress and Coping Models of Illness Adaptation When a child is first diagnosed with a chronic…
Fig. 1.1 WHO five dimensions of adherence. (Sabate 2003) De Civita and Dobkin’s (2004) triadic partnership model better captures this aspect of pediatric adherence . This model conceives of adherence…
Fig. 13.1 The comprehensive model of pediatric adherence promotion, showing patient flow from risk assessment through triage and intervention, to yearly reassessment Assessed Risk Triage is based on assessed risk…
Fig. 12.1 The pediatric psychosocial preventative health model. (PPPHM; Kazak 2006) For children with type 1 diabetes, our group developed and validated a 9-item interview to assess risk for poor…
Fig. 8.1 The ACE pyramid. http://www.cdc.gov/violenceprevention/acestudy/pyramid.html Adaptation to Stress Even when exposed to severe stressors, most people adapt reasonably well, without experiencing toxic stress or going on to develop more…
© Springer International Publishing Switzerland 2015David D. Schwartz and Marni E. AxelradHealthcare Partnerships for Pediatric AdherenceSpringerBriefs in Public Health10.1007/978-3-319-13668-4_6 6. Adherence in Adolescence David D. Schwartz1 and Marni E. Axelrad1 (1) Associate Professor of Pediatrics Department of…
