Implantation, Physiology of Placentation
Fig. 2.1 Schematic depiction of the possible role of interaction between several factors involved in the formation of the hypoxic placenta and its role in RPL. As shown, most complications…
Recurrent Pregnancy Loss: Definitions, Epidemiology, and Prognosis
Fig. 1.1 Trend lines demonstrate that as maternal age increases, live birth rate decreases, with a sharp decline at ~40 years. Ages are medians of ranges given in the literature…
The Common Characteristics Between Infertility and Recurrent Pregnancy Loss
Test Aim Performed Uterine assessment 2D Ult rasound Myometrium, endometrium, ovaries, pelvis RPL + infertility 3D Ultrasound Uterine cavity (congenital anomalies), myometrium, endometrium RPL + infertility Hysteroscopy Uterine cavity, myomas, endometrium (Ashreman syndrome)…
Endocrine Abnormalities in RPL
Fig. 3.1 Progestogen versus placebo/no treatment. Outcome 3 miscarriages (women with previous recurrent miscarriage only). [Adapted from Haas DM, Ramsey PS. Progestogen for preventing miscarriage. Cochrane Database Syst Rev. Has…
A Patient’s Perspective
© Springer International Publishing Switzerland 2016Asher Bashiri, Avi Harlev and Ashok Agarwal (eds.)Recurrent Pregnancy Loss10.1007/978-3-319-27452-2_13 13. A Patient’s Perspective Hildee Weiss1 (1) 2401 Blossom Lane, Beachwood, OH 44122, USA Hildee Weiss Email: gweiss@roadrunner.com KeywordsMiscarriageGrieving parentSupport As a…
Genetics of Recurrent Pregnancy Loss
Fig. 4.1 (a) An example of a reciprocal translocation involving chromosomes 16 and 22. The carrier parent can transmit an unbalanced translocation to the fetus. (b) An example of a…
The Health Caregiver’s Perspective: The Importance of Emotional Support for Women with Recurrent RPL
Fig. 12.1 Frida Kalo, 1929. This is how she drew the experience of her miscarriage. [Reprinted with permission from Frida Kahlo Museums Trust. Av. 5 de Mayo No. 2, Col….
Male Factors in Recurrent Pregnancy Loss
Fig. 8.1 Schematic representation of organization and compaction of sperm chromatin Nuclear Proteome of the Spermatozoa and Its Role in DNA Stability The first sign of sperm chromatin packaging is…
Contemporary Prevention and Treatment of Recurrent Pregnancy Loss
Fig. 11.1 Comparison of the distribution of causes . (a) 1676 patients in our previous study (based on data from Ref. [3]). (b) 482 patients with RPL, including those with…
Immunological Causes of Recurrent Pregnancy Loss
Biomarker Associated to RPL Prognostic value Needed research Autoantibodies Antiphospholipid antibodies +++ ++ Standardization of assays and cutoff values Prognostic studies in untreated patients Thyroid antibodies Antinuclear antibodies +++ ?…
