Abstract Poor fetal and neonatal nutrition interacts with the environment to produce subtle changes in the development, structure, and function of organs. Over the lifetime, these subtle changes alter an…
Brenda Poindexter, MD, MS Josef Neu, MD In this third edition of Gastroenterology and Nutrition: Neonatology Questions and Controversies , a number of emerging controversies have been identified by esteemed leaders in…
Abstract A growing amount of evidence suggests that specific components of parenteral nutrition (PN) are involved in the pathogenesis of intestinal failure-associated liver disease (IFALD). For a number of reasons,…
Abstract Short Bowel Syndrome is an entity that remains a challenge to clinicians. It also includes patients with intestinal failure whether or not they actually have a reduced length of…
Abstract A devastating disease that continues to remain poorly understood is neonatal necrotizing enterocolitis (NEC). This is a gastrointestinal disease that mostly affects premature infants; the risk of development is…
Abstract History of Donor Milk Current State of Milk Banking Nutrient and Bioactive Composition of Donor Milk Strengths and Challenges of Conducting and Comparing Donor Milk Trials Outcomes of Randomized…
Abstract Surgical procedures are not infrequent among patients admitted to regional neonatal intensive care units. Adequate nutrition in the newborn period, especially during times of critical illness and “stress,” is…
Abstract Human milk oligosaccharide (hMOS) is a major component of human milk—typically, the third most abundant solid constituent. The oligosaccharides of human milk are 3 to 32 sugars in size,…
Abstract Gastrointestinal motility in human infants is a complex function and is dependent on sensory and motor regulation of the intrinsic enteric nervous system integrated and modulated by the central…
Abstract Lipids and fatty acids are critical for optimal cell physiology, organ function, and neurodevelopment. Although these nutrients are delivered to the preterm infant, specific considerations and challenges unique to…
