The effect of magnesium sulfate on the activity of matrix metalloproteinase-9 in fetal cord plasma and human umbilical vein endothelial cells

Jul 6, 2017 by in GYNECOLOGY Comments Off on The effect of magnesium sulfate on the activity of matrix metalloproteinase-9 in fetal cord plasma and human umbilical vein endothelial cells

Objective Clinical evidence suggests that magnesium sulfate may reduce the risk of fetal neurologic injury in preterm delivery. Matrix metalloproteinase-9 (MMP-9) levels are elevated in preterm labor patients. There is…

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Maternal blood mitochondrial DNA content during normal and intrauterine growth restricted (IUGR) pregnancy

Jul 6, 2017 by in GYNECOLOGY Comments Off on Maternal blood mitochondrial DNA content during normal and intrauterine growth restricted (IUGR) pregnancy

Objective We investigated mitochondrial DNA (mtDNA) content in the maternal circulation of normal pregnancies of different gestational ages and in pregnancies complicated by intrauterine growth restriction (IUGR). Study Design We…

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Increased placental XIAP and caspase 3 is associated with increased placental apoptosis in a baboon model of maternal nutrient reduction

Jul 6, 2017 by in GYNECOLOGY Comments Off on Increased placental XIAP and caspase 3 is associated with increased placental apoptosis in a baboon model of maternal nutrient reduction

Objective Our objective was to determine signaling molecules and apoptosis rate in the term placenta of a baboon model of maternal nutrient reduction (MNR). Study Design Female baboons were fed…

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The effect of tumor-associated protein RCAS1 gene silencing on blood pressure and urinary protein excretion in pregnant mouse: a pilot study

Jul 6, 2017 by in GYNECOLOGY Comments Off on The effect of tumor-associated protein RCAS1 gene silencing on blood pressure and urinary protein excretion in pregnant mouse: a pilot study

Objective The level of tumor-associated receptor-binding cancer antigen that is expressed on SiSo cells (RCAS1) is decreased significantly in preeclamptic pregnancies. We hypothesized that RCAS1 protein gene silencing might affect…

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Mutations in the hepatocyte nuclear factor-1β( HNF1B)gene are common with combined uterine and renal malformations but are not found with isolated uterine malformations

Jul 6, 2017 by in GYNECOLOGY Comments Off on Mutations in the hepatocyte nuclear factor-1β( HNF1B)gene are common with combined uterine and renal malformations but are not found with isolated uterine malformations

Objective Congenital uterine abnormalities are common and may be associated with developmental renal abnormalities. Mutations of the hepatocyte nuclear factor-1β ( HNF1B) gene are associated with renal and uterine abnormalities….

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