Short telomeres may play a role in placental dysfunction in preeclampsia and intrauterine growth restriction

Jul 7, 2017 by in GYNECOLOGY Comments Off on Short telomeres may play a role in placental dysfunction in preeclampsia and intrauterine growth restriction

Objective Telomeres shorten and aggregate with cellular senescence and oxidative stress. Telomerase and its catalytic component human telomerase reverse-transcriptase regulate telomere length. The pathogenesis of preeclampsia and intrauterine growth restriction…

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Prevalence, incidence, and natural history of simple ovarian cysts among women >55 years old in a large cancer screening trial

Jul 7, 2017 by in GYNECOLOGY Comments Off on Prevalence, incidence, and natural history of simple ovarian cysts among women >55 years old in a large cancer screening trial

Objective The purpose of this study was to measure the occurrence and natural history of simple ovarian cysts in a cohort of older women. Study Design Simple cysts were ascertained…

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Metformin regresses endometriotic implants in rats by improving implant levels of superoxide dismutase, vascular endothelial growth factor, tissue inhibitor of metalloproteinase-2, and matrix metalloproteinase-9

Jul 7, 2017 by in GYNECOLOGY Comments Off on Metformin regresses endometriotic implants in rats by improving implant levels of superoxide dismutase, vascular endothelial growth factor, tissue inhibitor of metalloproteinase-2, and matrix metalloproteinase-9

Objective We sought to test if metformin could regress endometriotic explants in rats. Study Design After inducing endometriotic implants and randomization of female Wistar albino rats, they were given 25…

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Route of delivery and neonatal birth trauma

Jul 7, 2017 by in GYNECOLOGY Comments Off on Route of delivery and neonatal birth trauma

Objective We sought to examine rates of birth trauma in 2 groupings (all International Classification of Diseases, Ninth Revision codes for birth trauma, and as defined by the Agency for…

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