Williams-Beuren syndrome: the prenatal phenotype

May 25, 2017 by in GYNECOLOGY Comments Off on Williams-Beuren syndrome: the prenatal phenotype

Using prenatal BACs-on-Beads technology, the first prenatal case of Williams-Beuren syndrome (WBS) was diagnosed. In light of this result, an ultrasound scan confirmed the presence of well-characterized features of WBS….

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Placental mesenchymal dysplasia

May 25, 2017 by in GYNECOLOGY Comments Off on Placental mesenchymal dysplasia

Placental mesenchymal dysplasia is a benign condition that can be confused with a molar pregnancy by ultrasound scanning and gross examination. Conservative management should be considered with a normal-appearing singleton…

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Laparoscopic management of cornual pregnancy

May 25, 2017 by in GYNECOLOGY Comments Off on Laparoscopic management of cornual pregnancy

Problem: risks for hemorrhage and infertility Clinical and ultrasound examinations raised suspicion for an ectopic pregnancy in a 42-year-old woman. She had a history of right salpingectomy because of a…

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An unexpected obstacle

May 25, 2017 by in GYNECOLOGY Comments Off on An unexpected obstacle

Case notes A 29-year-old woman, at 40 weeks’ gestation in her first pregnancy, was admitted to the maternity ward, and labor was induced with prostaglandins. Surprisingly, a subsequent vaginal examination…

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Hydroxychloroquine reduces binding of antiphospholipid antibodies to syncytiotrophoblasts and restores annexin A5 expression

May 25, 2017 by in GYNECOLOGY Comments Off on Hydroxychloroquine reduces binding of antiphospholipid antibodies to syncytiotrophoblasts and restores annexin A5 expression

Objective Antibody-mediated disruption of the annexin A5 anticoagulant shield has been posited to be a thrombogenic mechanism in the antiphospholipid syndrome. We recently showed that the antimalarial drug, hydroxychloroquine, dissociates…

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