Antiretroviral Pharmacology in Pregnant Women and Newborns Mark Mirochnick Brookie M. Best Introduction As infection with human immunodeficiency virus (HIV) continues to spread throughout the world, HIV/AIDS has become a…
Drugs and Perinatal Brain Injury Maria Delivoria-Papadopoulos AgustÃn Legido Ignacio Valencia Om Prakash Mishra Severe fetal asphyxia may have a broad range of effects on the brain from no evident…
Pharmacologic Treatment of Neonatal Apnea Girija Natarajan Jose Maria Lopes J. V. Aranda Methylxanthines Since the initial report in 1973 of a decrease in the frequency of apneic episodes in…
Drugs and Lung Development Alan H. Jobe John P. Newnham Lung development is a target for drug therapy only within the context of prematurity. Corticosteroids are standard of care for…
Drugs for Hyperbilirubinemia David K. Stevenson Ronald J. Wong Susan R. Hintz Hendrik J. Vreman Introduction Hyperbilirubinemia is a natural and essentially ubiquitous transitional phenomenon among human newborns. Approximately 60%…
The Excretion of Drugs and Chemicals in Human Milk Cheston M. Berlin Jr. Introduction During the 1960s and the early 1970s, the incidence of breastfeeding reached a nadir; in 1972…
Renal Function and Excretion of Drugs in the Newborn John N. van den Anker Karel Allegaert A thorough understanding of the developmental changes in neonatal renal function is needed to…
Perinatal Origins of Adult Defects in Drug Metabolism Bernard H. Shapiro One of the hot topics in medicine today is the so-called fetal origins of adult diseases. This intriguing topic…
Principles of Neonatal Pharmacology Jeffrey L. Blumer Michael D. Reed Introduction The history of drug therapy is replete with examples of adverse reactions to drugs in children. Virtually all the…
Maternal Drug Intake and the Newborn Nada Djokanovic Rada Boskovic Gideon Koren Introduction The use of prescription drugs during pregnancy has become a concern since the thalidomide tragedy. However, medication…
