I. Predominantly large vessel vasculitis Takayasu arteritis II. Predominantly medium-sized vessel vasculitis Kawasaki disease Childhood polyarteritis nodosa Cutaneous polyarteritis III. Predominantly small vessel vasculitis A. Granulomatous Granulomatosis with polyangiitis (GPA),…
Connective tissue disorders Systemic lupus erythematosus Dermatomyositis Scleroderma Bullous disorders Linear immunoglobulin A bullous dermatosis Bullous pemphigoid Pemphigus vulgaris Dermatitis herpetiformis Erythema multiforme Vasculitis Polyarteritis nodosa Henoch–Schönlein purpura Granulomatous vasculitides…
Fig. 1 Steroid regimen as proposed by the Childhood Arthritis and Rheumatology Research Alliance for juvenile systemic lupus erythematosus In maintenance therapies, steroids are usually continued at a low dose…
© Springer International Publishing Switzerland 2015Rolando Cimaz (ed.)Systemic Corticosteroids for Inflammatory Disorders in Pediatrics10.1007/978-3-319-16056-6_14 Corticosteroids in Neonatology: Postnatal Corticosteroids in Preterm Infants with Bronchopulmonary Dysplasia Silvia Perugi1 and Carlo Dani1 (1) Division of Neonatology, Careggi…
© Springer International Publishing Switzerland 2015Rolando Cimaz (ed.)Systemic Corticosteroids for Inflammatory Disorders in Pediatrics10.1007/978-3-319-16056-6_13 Corticosteroids in Pediatric Nephrology Kjell Tullus1 (1) Nephrology, Great Ormond Street Hospital for Children, Great Ormond Street, London, WC1N 3JH,…
© Springer International Publishing Switzerland 2015Rolando Cimaz (ed.)Systemic Corticosteroids for Inflammatory Disorders in Pediatrics10.1007/978-3-319-16056-6_12 Systemic Corticosteroids in Respiratory Diseases in Children Chiara Caparrelli1, Claudia Calogero1 and Enrico Lombardi1 (1) Paediatric Pulmonary Unit, “Anna Meyer” Paediatric University-Hospital,…
Fig. 1 Regulation of the hypothalamic–pituitary–adrenal axis. Adrenal cortisol production and secretion are regulated by the hypothalamic–pituitary–adrenal axis. Basal diurnal rhythm (regulated by internal clock genes) and various stress factors…
(1) Section of Pharmacology, Department of Medicine, University of Perugia, Building D, 2nd floor, Severi Square 1, San Sisto, Perugia, I-06132, Italy Giuseppe Nocentini Email: giuseppe.nocentini@unipg.it Introduction Owing to…
Fig. 1 Molecular mechanism of glucocorticoid action. GR glucocorticoid receptor, GC glucocorticoid, HSP heat-shock protein, FKBP FK506-binding protein, NF-kB nuclear factor-kB Genetic and Epigenetic Predictors of GC Response Given the…
2. Zetterstrom R (2008) The discovery that cortisone may effectively ameliorate inflammatory and allergic disease. Acta Paediatr 97:513–517PubMedCrossRef 3. Hench PS (1938) The ameliorating effect of pregnancy on chronic atrophic…
