Pathological agent Lesion Site Morphology Bacteria Staphylococcus aureus Abscess Any, bone Cocci Gram + Streptococcus spp. Abscess Skin, any Cocci Gram + Mycobacteria tub. Tuberculoma Any any Granul. Patterns, Zielh+…
Predisposing disease Tumors Neurofibromatosis type 1 (NF1 gene mutation) Neurofibroma, Schwannoma, MPNST, GIST Rhabdomyosarcoma Hereditary retinoblastoma (RB1 gene mutation) Bone and soft tissue sarcomas Antineoplastic treatment (radiotherapy, alkylating agents) Sarcomas…
Fig. 4.1 Neuroblastoma . Poorly differentiated neuroblastoma . No neuropil. Elevated MKI. MGG Fig. 4.2 Neuroblastoma. Maturating neuroblastoma . Some larger cells with cytoplasm. MGG Fig. 4.3 Neuroblastoma. Neuropil and…
Fig. 5.1 Desmoid fibromatosis . Long fascicular cohesive fragment of bland fibroblasts and scattered uniform fibroblasts, some with cytoplasmic processes, May-Grünwald Giemsa (MGG) Fig. 5.2 Desmoid fibromatosis. Loosely cohesive cluster…
Fig. 3.1 (a) A low-power view of embryonal RMS featuring tissue fragments with stroma and numerous dissociated rhabdomyoblasts. (b) Two large tissue fragments containing stroma and tumor cells. (a) Giemsa,…
Anatomic sites Main histopathological subtypes Posterior fossa (cerebellum, fourth ventricle and brainstem) Medulloblastoma Atypical teratoid/rhabdoid tumor (AT/RT) Pilocytic astrocytoma Ependymoma Brainstem diffuse glioma Cerebral hemispheres Ganglioglioma (temporal lobe) Pleomorphic xanthoastrocytoma…
Fig. 7.1 UCNT, Regaud type , isolated tumor cells and inflammatory background, May-Grünwald Giemsa (MGG) Fig. 7.2 UCNT, Schminke type, spindle-shaped cells, Papanicolaou 7.1.3 Ancillary Techniques Immunocytochemistry (ICC) shows positivity…
Fig. 6.1 Epithelioid sarcoma. Polymorphous epithelioid with rhabdoid features , May-Grünwald-Giemsa (MGG) Fig. 6.2 Epithelioid sarcoma . Polymorphous epithelioid cells , Papanicolaou Fig. 6.3 Epithelioid sarcoma. Epithelioid cells mimicking carcinoma…
Fig. 9.1 Classical Hodgkin Lymphoma featuring one Reed-Sternberg cell surrounded by an inflammatory background. There are five eosinophils in the field. MGG ×60 RS cells may be bi-nucleated or may…
Thyroid carcinomas Other thyroid tumors Papillary carcinoma Teratoma Follicular carcinoma Primary lymphoma and plasmacytoma Poorly differentiated carcinoma Ectopic thymoma Undifferentiated (anaplastic) carcinoma Angiosarcoma Squamous cell carcinoma Smooth muscle tumors Mucoepidermoid…
