Alterations P53 signature Serous tubal intraepithelial lesion (STIL) Serous tubal intraepithelial carcinoma (STIC) High-grade serous carcinoma P53 Mutated (LOH) Mutated Mutated (LOH) Mutated (LOH) BRCA1/BRCA2 Mutated/LOH Mutated/LOH/hypermethylated Genes (FISH) CCNE1…
Fig. 13.1 HSIL/CIN3 and atypical mitotic figure. Nuclear atypia extends through the full epithelial thickness without any cytoplasmic maturation in the superficial epithelial layers. Note the nuclear size and nuclear/cytoplasmic…
Fig. 2.1 (a) Ovarian cyst with surface involvement by friable papillary excrescences. They appear to cover most of the ovarian cyst surface. (b) The inner lining of the same ovarian…
Author # Complex atypical hyperplasia # Endometrial carcinoma Agents used Response rate (%) Median follow-up months (range) Ferenczy (1989) 20 0 MPA 50 5.5 years (2–7 years) Randall (1997) 17…
