Obgyn Key

Clinical Manifestations • Fatigue, IUGR, preterm deliv, perinatal mortality, pica, restless leg syn • Hb <6 g/dL a/w NRFHT, oligohydramnios, fetal death, CHF (Hb <4 g/dL) • Signs: Pallor (conjunctiva),…

CERVICAL CANCER Epidemiology (CA Cancer J Clin 2011;61:212) • 2nd most common cancer in women worldwide • Mean age at dx: 40–59 y; bimodal distribution peaks 35–39 y & 60–64…

Cancer Screening Guidelines • Cervical dysplasia: See below • Breast cancer: See below (Obstet Gynecol 2011;118:372) • Colorectal cancer: Begin age 50 yo. Consider 45 yo if AA. Younger if…

Hormones of Pregnancy • hCG is secreted by placental trophoblast. Detected in the mother’s bld 8 d after conception. Maintains corpus luteum progesterone production. Structurally similar to LH, FSH, &…

Cardiovascular Changes in Pregnancy Blood Volume • Plasma vol ↑ 45% from 6–32 w gest to 4700–5200 mL • RBC mass ↑ by 20–30% (from ↑ production of RBCs) •…

Testing Modalities (Obstet Gynecol 2009;113:687) • Fetal mvmt count (“kick count”) (Cochrane Database Syst Rev 2007:CD004909) Variable protocols, usually 2 h, 3–7× per week 10 mvmts → reassuring; insuff evid…

Clinical Manifestations (NEJM 2006;355:1244) • BV: Copious, thin, whitish-gray, fishy-smelling discharge. Less likely pruritus. • Candidiasis: Thick, white, curdy discharge. No odor. + Pruritus, dysuria, vaginal erythema. • Trichomonas: Copious…

CHOLELITHIASIS Epidemiology • 10–15% prevalence in adults overall; 1–3% of pregnant women • Risk factors: Preg (impaired gallbladder emptying, increased biliary sludge); ↑ estrogen (gender [ 2× > ], obesity,…

> , slightly. Decreases w/ age. • 75% of primary HA will ↓ in Preg. ∼40% PP → HA, esp 1st w. Pathogenesis • 90% are tension-type, migraine, or cluster…

Clinical Findings & Exam • Uremia, oliguria/anuria, hematuria • Prerenal: Tachy, dry mucous membranes, orthostatic HoTN • Intrarenal: Pulm hemorrhage, palpable purpura → vasculitis + glomerulonephritis, livedo reticularis → atheroembolic…