Supplement to September 2012 (vol. 207, no. 3, page S63)
Jacobs AL. Liability and maternal immunization: in utero injury claims in the VICP. Am J Obstet Gynecol 2012;207:S63-6. Because the author is employed by the US Government, which holds the…
Oncogenic PIK3CA gene mutations and HER2/neu gene amplifications determine the sensitivity of uterine serous carcinoma cell lines to GDC-0980, a selective inhibitor of Class I PI3 kinase and mTOR kinase (TORC1/2)
Objective To evaluate PIK3CA mutational status and c-erbB2 gene amplification in a series of primary uterine serous carcinomas (USC) cell lines. To assess the efficacy of GDC-0980, a potent inhibitor…
Patient preferences for uterine preservation and hysterectomy in women with pelvic organ prolapse
Objective The purpose of this study was to describe patient preferences for uterine preservation and hysterectomy in women with pelvic organ prolapse symptoms and to describe predictors of preference for…
Risk factors for maternal and fetal outcome in pregnancy complicated by Ebstein anomaly
Objective The goal of the study was to examine risks in pregnancy in patients with Ebstein anomaly. Study Design Data were examined retrospectively for 13 patients (27 pregnancies, 21 live…
Risk-adjusted models for adverse obstetric outcomes and variation in risk-adjusted outcomes across hospitals
Objective Regulatory bodies and insurers evaluate hospital quality using obstetrical outcomes, however meaningful comparisons should take preexisting patient characteristics into account. Furthermore, if risk-adjusted outcomes are consistent within a hospital, fewer…
Methylergonovine maleate and the risk of myocardial ischemia and infarction
Objective The purpose of this study was to examine the risks of acute coronary syndrome (ACS) and acute myocardial infarction (AMI) that are associated with methylergonovine maleate (Methergine; Novartis Pharmaceuticals…
Hypertension in pregnancy is associated with elevated homocysteine levels later in life
Objective Hyperhomocysteinemia is associated with an elevated cardiovascular disease risk. We examined whether women with a history of hypertension in pregnancy are more likely to have a high level of…
Maternal preeclampsia and bone mineral density of the adult offspring
Objective Preterm birth at very low birthweight (<1500 g) is associated with cardiometabolic risk factors and reduced bone mineral density in the adult offspring. Preeclampsia is a frequent cause of…
Incidence, risk factors, and temporal trends in severe postpartum hemorrhage
Objective Because the diagnosis of postpartum hemorrhage (PPH) depends on the accoucheur’s subjective estimate of blood loss and varies according to mode of delivery, we examined temporal trends in severe…
Prediction of cesarean delivery using the fetal-pelvic index
Objective The purpose of this study was to estimate the usefulness of the fetal-pelvic index (FPI) in the prediction of cesarean delivery among nulliparous and women who undergo a trial…
