Mutation analysis of papillary tubal hyperplasia associated with ovarian atypical proliferative serous tumor and low-grade serous carcinoma

May 13, 2017 by in GYNECOLOGY Comments Off on Mutation analysis of papillary tubal hyperplasia associated with ovarian atypical proliferative serous tumor and low-grade serous carcinoma

We present a patient with ovarian atypical proliferative serous tumor and low-grade serous carcinoma, related to KRAS mutation. Bilateral fallopian tubes had papillary tubal hyperplasia, providing additional evidence that it…

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Differences in cortical development assessed by fetal MRI in late-onset intrauterine growth restriction

May 13, 2017 by in GYNECOLOGY Comments Off on Differences in cortical development assessed by fetal MRI in late-onset intrauterine growth restriction

Objective The objective of the study was to evaluate cortical development parameters by magnetic resonance imaging (MRI) in late-onset intrauterine growth–restricted (IUGR) fetuses and normally grown fetuses. Study Design A…

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Maternal metformin treatment decreases fetal inflammation in a rat model of obesity and metabolic syndrome

May 13, 2017 by in GYNECOLOGY Comments Off on Maternal metformin treatment decreases fetal inflammation in a rat model of obesity and metabolic syndrome

Objective Obesity and metabolic syndrome are associated with systemic inflammation and increased perinatal morbidity. Metformin improves metabolic and inflammatory biomarkers in nonpregnant adults. Using in vivo and in vitro models, we examined…

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Reply

May 13, 2017 by in GYNECOLOGY Comments Off on Reply

We thank Drs Reiss and Cherry for their interest in our article and the important points they have raised in their letter. Cell free DNA testing has the highest detection…

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A foot path to diagnosis

May 13, 2017 by in GYNECOLOGY Comments Off on A foot path to diagnosis

Case notes A routine anatomical survey performed at 21 weeks’ gestation in a 34 year old multiparous Asian woman revealed a female fetus with thickening of the dorsal aspect of…

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Reply

May 13, 2017 by in GYNECOLOGY Comments Off on Reply

We thank Dr Moise et al for their interest and congratulations for our Society for Maternal-Fetal Medicine (SMFM) clinical guideline on twin-twin transfusion syndrome. Dr Moise et al have a concern that…

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