Fig. 7.1 Changes in total body bone mineral content (BMC) at discharge (2 months) and at 6 months post-burn, expressed as a percentage of baseline (admission) values. Data are shown…

Fig. 11.1 Panoramic radiograph of a 31-year-old male patient with giant cell tumors of the right maxilla and mandible (arrows). The lesions are associated with root resorption of the adjacent…

Class Drug Route of administration Timing Mechanism of action Antiresorptive Denosumaba Subcutaneously Twice yearly Decreases bone resorption by inhibiting RANKL Osteoanabolic PTH(1-34) (teriparatide)b Subcutaneously, transdermal, chip Daily, weekly Increase bone…

Bruck Syndrome (OMIM 259450) Inheritance: Autosomal recessive. Genetic defect: 1. Mutations in PLOD2 gene (probably located in the chromosome 17p12 region) resulting in deficiency of a bone-specific telopeptidyl lysyl hydroxylase…

Fig. 4.1 Growth of long bones. Schematic diagram illustrating the growth of long bones: (a) Longitudinal growth occurs due to hypertrophic differentiation of growth plate chondrocyte. (b) Bone morphology is…

Fig. 5.1 Molecular structure of bisphosphonates. The generic bisphosphonate structure (left) with two phosphonate groups binding to a central carbon atom. Modern bisphosphonates have a hydroxyl group and specific nitrogen-containing…

Fig. 8.1 Stimulation and action of intrinsic GH. GH is secreted in the pituitary gland and stimulated by hypothalamic hormones, such as GHRH and ghrelin, and is suppressed by somatostatin….

Fig. 10.1 Molecular structure of D2 and D3 Table 10.1 Food sources of vitamin D and calcium Dietary sources of calcium and vitamin D Calcium content Vitamin D content Breast…