Disease related Neuropathy secondary to uncontrolled diabetes mellitus Tumor infiltration and nerve impingement Gynecologic malignancy-specific pain syndromes Lumbosacral plexopathy Pelvic pain Malignant psoas syndrome Treatment related Radiation-induced pain (e.g., proctitis,…
Fig. 38.1 CT scan showing enlarged uterus with cystic spaces and thinned out myometrium A differential diagnosis of uterine sarcoma/endometrial malignancy was made on imaging. CA125 and LDH were within…
Study Stage Number Clinical outcome Kapp et al. [8] I 951 5-year DSS: 76 % II 43 5-year DSS: 60 % III 99 5-year DSS: 45 % IV 303 5-year…
SERM Breast Uterus Tamoxifen − ++ Raloxifene − − Toremifene − +/− Idoxifene − +/− Droloxifene − +/− GW 5638 − +/− Arzoxifene − − EM-652 − +/− Many of…
Stage 5 years survival (%) 1A 88 1B 75 11 69 111A 58 111B 50 111C 47 1v A 17 1v B 15 Types of the Tumor There are two…
NCEP-ATPIII [75] Modified WHO [9] EGIR [76] AACE [77] IDF [1] Simplified definition of metabolic syndrome [78] Mandatory … Insulin resistancea >75th percentile glucose ≥110 mg/dL; 2 h glucose…
Characteristic Type I Type II Chronic estrogenic stimulation Present (hormone dependent) Absent (not hormone dependent) Growth Slow growing Rapid Precursor lesion Atypical hyperplasia Endometrial intraepithelial carcinoma Age at initial diagnosis…
Fig. 15.1 Lymph node evaluation road map. SLN, sentinel lymph node; LND, lymphadenectomy Sentinel Lymph Nodes and Endometrial Cancer The first reported use of SLN mapping in endometrial cancer was…
Mesenchymal tumors Mixed epithelial and mesenchymal tumors Endometrial stromal and related tumors Carcinosarcoma Endometrial stromal sarcoma, low grade Adenosarcoma Endometrial stromal nodule Carcinofibroma Undifferentiated stromal sarcoma Adenofibroma Smooth muscle tumors…
Drug Dose Response rate (%) Cisplatin 50–100 mg/m2 every 3 weekly 18–27 Doxorubicin 50–60 mg/m2 every 3 weekly 22–32 Paclitaxel 175–250 mg/m2 every 3 weekly 36 In order to improve…
