Thrombophilia and Thrombosis
Maternal risk factors Age >35 years BMI > 30 kg/m2 Black race Cigarette smoker IV drug user Medical comorbidities: Infection, dehydration, diabetes, malignancy, autoimmune disease, varicose veins, sickle cell, nephrotic syndrome, hypertension…
Cardiac Disease
High-risk conditions Intermediate-risk conditions Low-risk conditions Severe systemic ventricular dysfunction (LVEF < 30 % OR NYHA III and IV) Uncorrected cyanosis, repaired complex CHD Repaired simple congenital heart disease without residual cardiac…
The Care and Management of Rheumatologic Disease in Pregnancy
Autoimmune disease Behavior during pregnancy Risk of active maternal disease on pregnancy Drugs used during the nonpregnant state Drugs that can be used during pregnancy Rheumatoid arthritis Improves in 50–75…
Diabetes and Pregnancy
Fetal and infant risks Maternal risks Miscarriage or stillbirtha Congenital anomaliesa • Caudal regression syndrome • CNS abnormalities—spina bifida, anencephaly, hydrocephalous • Cardiac Macrosomia Organomegaly Hypoxic events including intrauterine fetal demise Operative delivery…
Headaches and Seizures
Cause of headache Common features Treatment in pregnancy Treatment postpartum Migraine Frontal (often unilateral), prolonged, and pulsatile Other: nausea, vomiting, and aversion to loud noise, bright light, and physical activity…
Mood Disorders
A. Five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either…
Interstitial Pregnancy
Fig. 11.1 Transvaginal ultrasound (TVUS). a An empty uterine cavity (UC) with echogenic line (arrows) leading towards gestational sac (P). b 3D TVUS rendering showed thin myometrial edge marked with…
Inadvertent Methotrexate Administration
Fig. 9.1 Note short forearms (From Seidahmed et al., A Case of methotrexate embryopathy with holoprosencephaly, expanding the phenotype, Birth Defects Research (Part A) 2006;76:138–142. Reproduce with permission.) Fig. 9.2…