Drug Mechanism of action Common toxicities Less common toxicities Dose ranges Penetration of blood–brain barrier Intravenous Vincristine Vinca alkaloid Constipation, diarrhea, peripheral neuropathy SIADH, paralytic ileus, seizures, severe jaw pain…
Fig. 15.1 Sagittal T1 + gadolinium and coronal T1 + gadolinium sequences of a left large parietal ATRT Pathology As described in Chap. 6, the consistent histologic feature of ATRT…
Fig. 10.1 (a–c) A 12-year-old female with GBM. (a) Axial T1, (b) axial T1 with gadolinium, (c) axial T2. (d–f) A 15-year-old male with malignant glioma. (d) Axial T1, (e)…
Fig. 8.1 Bilateral acoustic neuroma in NF2 Patients with NF2 can also develop intracranial, spinal, and optic nerve sheath meningiomas, ependymomas, and gliomas of the CNS. Most meningiomas of the…
Fig. 7.1 Summary of molecular subgroups and recurrent genomic alterations identified in pediatric brain tumors Integrated genomic studies have revealed that MB comprises at least four molecular variants, which are…
© Springer Science+Business Media New York 2015Katrin Scheinemann and Eric Bouffet (eds.)Pediatric Neuro-oncology10.1007/978-1-4939-1541-5_3 3. Epidemiology of Central Nervous System Tumors Daniel L. Keene1 and Donna L. Johnston2 (1) Department of Pediatrics, Children’s Hospital of Eastern Ontario, Ottawa, ON, Canada…
Neurooncology (chair) Case managers/nurses Neurosurgery (chair) Social work Neuroradiology Physiotherapy Neuropathology Occupational therapy Radiation oncology (chair) Dietician Neuroophthalmology
© Springer Science+Business Media New York 2015Katrin Scheinemann and Eric Bouffet (eds.)Pediatric Neuro-oncology10.1007/978-1-4939-1541-5_5 5. Neurosurgery Sami Obaid1, Pierre-Olivier Champagne2, Claude Mercier1 and Louis Crevier1 (1) Department of Neurosurgery, Centre Hospitalier Universitaire de Sainte-Justine, Montréal, QC, Canada (2) Department of…
© Springer Science+Business Media New York 2015Katrin Scheinemann and Eric Bouffet (eds.)Pediatric Neuro-oncology10.1007/978-1-4939-1541-5_2 2. Presentation of Central Nervous System Tumors Ali Amid1, Daniel L. Keene2 and Donna L. Johnston1 (1) Department of Pediatrics, Division of Hematology/Oncology, Children’s Hospital of Eastern…
(1) Department Obstetrics & Gynaecology, St George Hospital, Kogarah, New South Wales, Australia Abstract Urodynamic testing is an invasive procedure. At the minimum, a urethral catheter and a rectal…
