Vascular Development in the Zebrafish
Fig. 2.1 Arterial and venous precursor cell migration. a At 12 hpf, angioblasts are located within the anterior and posterior lateral plate mesoderm (LPM) in two bilateral stripes. Presumably, even at…
Pericytes in Vascular Development and Function
Fig. 3.1 Association of pericytes and endothelial cells. a Schematic representation of endothelial cells (blue) and mural cells (pink). Vascular smooth muscle cells cover larger vessels such as arterioles. In…
Nitric Oxide Synthesis in Vascular Physiology and Pathophysiology
Fig. 16.1 Antihypertensive, antithrombotic, and antiatherosclerotic effects of endothelial nitric oxide synthase (eNOS). The eNOS enzyme in endothelial cells (ECs) can be activated by shear stress or agonists such as…
Fibroblast Growth Factor Signaling in Vascular Development
Fig. 4.1 Fibroblast growth factor receptor 1 (FGFR1) signal transduction. The binding of FGF-1, -2, or -4 at the interface of the IgII and IgIII domains, together with the binding…
More than a Scaffold: Extracellular Matrix in Vascular Signaling
Fig. 7.1 Extracellular matrix (ECM) ligands and receptors. Both ECM ligands and receptors typically possess modular structure, containing domains that allow them to bind to each other as well as…
Cytochrome P450-Derived Lipid Mediators and Vascular Responses
Fig. 9.1 Cytochrome P450 (CYP)-dependent metabolism of n-6 (arachidonic and linoleic acid) and n-3 (eicosapentaenoic and docosahexaenoic acid), and metabolism of the epoxides generated to the corresponding diols by the…
Junctional Signaling in Endothelial Cells
Junction stabilization Small GTPase Effectors Molecular function GEF Rap1 a Epac a (cAMP-dependent) PDZ-GEF 1 a (cAMP-independent) C3G b Stabilization of VE-cadherin at junctions Rac Tiam (Rac specific)…
Development and Differentiation of the Lymphatic Vascular System
Fig. 5.1 Lymphatic vessel basics. Interstitial fluid and immune cells pass through discontinuous adherens junctions on lymphatic capillaries in a unidirectional manner. One of the main markers for lymphatic capillaries…
Practical Mammography
Fig. 21.1 Left CC IR at IMF Fig. 21.2 Left CC IMF plus 2 cm Handy Hints In order to achieve maximum breast footprint and optimum compression force balance between…
Other Breast Diseases
Fig. 4.1 Cysts. Medio-Lateral Oblique (MLO) view showing multiple ovoid/lobulated lesions (arrow). Parenchymal structures can be seen through the lesion. The low density, ovoid shape and partial halo suggest a…
