Unsolved problems Possible solutions Advantages/drawbacks Uncontrolled LH surge Flexible scheduling Very challenging GnRH antagonists Additional cost, inefficient? Low-dose clomiphene Endometrial effect? Premature ovulation NSAIDs Cheap, efficient Empty follicle Follicular flushing…
Fig. 14.1 Protocol for minimal stimulation and natural cycle IVF. GnRHa GnRH agonist, OR oocyte retrieval, ET embryo transfer, Cryo cryopreservation Method for Determining the Oocyte Retrieval Period After confirming follicular…
Fig. 25.1 Immature oocyte with compacting cumulus cells surrounding the oocyte In Vitro Maturation of Immature Oocytes The source of immature is the most critical point for oocyte maturation, but the…
Fig. 4.1 Human germinal vesicle (a) and metaphase I (b) oocytes. Mitochondria are absent from the cortical region of the cytoplasm in germinal vesicle oocytes while they are dispersed in the…
Fig. 27.1 Detailed protocol for natural cycle IVF combined with IVM treatment (Based on Lim et al. [27] with modification) In addition, it has been reported that the clinical outcomes of…
Characteristics from 1187 pregnancies Singleton pregnancies (n = 960) Twin gestation pregnancies (n = 221) Triplet gestation pregnancies (n = 5) Quadruplet gestation pregnancies (n = 1) Mean gestational age at delivery (weeks + days) 37 + 4 36 + 5 35 + 2 29 + 0 No….
Gene Genotype associated with RIF Genotype associated with RM Ethnicity Other associated phenotypes Apo E Nil E2, E3, E4 [34] Asian, Caucasian Higher LDL cholesterol ACE Nil Insertion, deletion [35]…
© Springer International Publishing AG 2017Ri-Cheng Chian, Geeta Nargund and Jack Y. J. Huang (eds.)Development of In Vitro Maturation for Human Oocytes10.1007/978-3-319-53454-1_18 18. Mild Stimulation Protocols for Oncofertility Patients William L. Ledger1 , Nur Atiqah Hairudin1 and Chan Soke Yee Sara1 (1) Department of…
© Springer International Publishing AG 2017Ri-Cheng Chian, Geeta Nargund and Jack Y. J. Huang (eds.)Development of In Vitro Maturation for Human Oocytes10.1007/978-3-319-53454-1_16 16. Mild Stimulation Protocol for Poor Ovarian Responders Undergoing IVF Alberto Revelli1 , Simona Casano1 and Chiara Benedetto1…
© Springer International Publishing AG 2017Ri-Cheng Chian, Geeta Nargund and Jack Y. J. Huang (eds.)Development of In Vitro Maturation for Human Oocytes10.1007/978-3-319-53454-1_17 17. The Application of Mild Stimulated Cycle IVF in Primary Ovarian Insufficiency Jie Wu1 (1)…
