Impact on Fertility Outcome
Fig. 14.1 The effect of prednisone on immunocompetent cells in men with positive sperm-agglutinating antibodies in seminal plasma Increased pregnancy rate after various schemes of prednisone dosages is referred between…
Male Autoimmune Infertility
© Springer International Publishing Switzerland 2017Walter K.H. Krause and Rajesh K. Naz (eds.)Immune Infertility10.1007/978-3-319-40788-3_12 12. Male Autoimmune Infertility Felice Francavilla1 and Arcangelo Barbonetti2 (1) Department of Life, Health and Environmental Sciences, University of L’Aquila, Coppito, 67100 L’Aquila, Italy…
ASA in the Female
Fig. 10.1 The immune response to antigen (Ag) generates antibodies bearing unique idiotypic (Id) signatures comprising the antigen-binding site or paratope of the antibody [47]. The individual’s immune system subsequently…
Site and Risk Factors of Antisperm Antibodies Production in the Male Population
Chronic obstruction of the MRT Congenital Congenital bilateral absence of the vas deferens (CBAVD) Müllerian prostatic cysts Acquired Vasectomy Iatrogenic obstruction of the epididymis and/or ductus deferens Inflammation and/or infection…
Sperm-Specific T Lymphocytes
Fig. 7.1 Various populations of leukocytes in semen, as differentiated according to surface molecules. The surface molecules characterize the following cell populations: CD2 (T cell in general), CD3 (T cells…
Immune Chemistry of ASA
Fig. 6.1 Antioxidant therapy gradually diminishes sperm DNA fragmentation with concomitant ASA disappearance As far as the cross-reactivity of ASA antibodies is concerned, our earlier detailed work indicated that plethora…
The Immune Privilege of the Testis
Fig. 5.1 Hypothetical model of factors maintaining the testicular immune privilege. The blood-testis barrier (BTB) connects neighboring Sertoli cells (SC) and segregates the majority of neo-antigen expressing meiotic and postmeiotic…
Proteomic Analysis of Human Spermatozoa
Fig. 1.1 The power of proteomics. A proteomic comparison of tryptic peptides isolated from the spermatozoa of patients whose gametes lack a capacity to bind to the zona pellucida demonstrated…
Pathology and Genomics in Gestational Trophoblastic Neoplasia
Neoplasms Choriocarcinoma Placental site trophoblastic tumour Epithelioid trophoblastic tumour Molar pregnancies Hydatidiform mole • Complete • Partial • Invasive Non-neoplastic lesions Exaggerated placental site Placental site nodule and plaque Abnormal (nonmolar) villous lesions …
Molecular Pathology and Novel Therapy for Uterine Sarcomas
Fig. 9.1 Development of uterine neoplasms in Psmb9/β1i −/− mice. Uterine neoplasms in Psmb9/β1i −/− mice. Photographs of H&E staining and immunohistochemistry (IHC) with anti-ki-67/MIB1 antibody show the characters of…
