© Springer International Publishing Switzerland 2016Nanette F. Santoro and Amber R. Cooper (eds.)Primary Ovarian Insufficiency10.1007/978-3-319-22491-6_2 2. Etiologies of Primary Ovarian Insufficiency Nastaran Foyouzi1 , Lisa J. Green1 and Sally A. Camper2, 3 (1) Division of Reproductive Endocrinology and Infertility, OB &…
Affected organ APS-1 APS-2 APS-3 Adrenal gland Addison’s Disease Addison’s Disease – Parathyroid gland Hypoparathyroidism – – Mucocutaneous candidiasis – – Pancreas Rare Type 1 Diabetes mellitus – Liver Hepatitis…
Fig. 11.1 Netrins and their receptors in the vascular system. a Netrin family members show a structural homology to the β-laminin (Netrin4) or γ-laminin (Netrin1, 2, 3, and G) subunits….
Fig. 15.1 Selection of possible hypoxia-dependent mechanisms contributing to pulmonary vascular remodeling in chronic obstructive pulmonary disease-pulmonary hypertension (COPD-PH). Cigarette smoke-induced airway obstruction and emphysema can result in hypoxia. Hypoxia,…
Fig. 14.1 Domain structure for hypoxia-inducible factors (HIFs), prolyl hydroxylase domain proteins (PHDs), and factor-inhibiting HIF (FIH). a Schematic diagram of the HIF-1α, HIF-2α, and HIF-1α proteins and their functional…
Fig. 12.1 45 ° Fundus photograph of a 35 year old type 1 diabetic patient after 12 years of disease. No signs of diabetic retinopathy detectable One disease that frequently strikes in…
Fig. 10.1 a Distribution of tissue factor (TF) in the vessel wall. b Disturbance of the membrane asymmetry in the membrane of activated platelets enables Ca2+-dependent binding of coagulation factors…
Fig. 13.1 Angiopoietin functions in the vasculature. In the adult vasculature, angiopoietin-1 (Ang1) contributes to the stabilization of pre-existing vessels by providing a basal signal that leads to constitutive Tie2…
Fig. 8.1 Summary of signal transduction pathways operating downstream of vascular endothelial growth factor-A (VEGFA) in endothelial cells of relevance for vascular permeability in vivo . See text for details….
Fig. 2.1 Arterial and venous precursor cell migration. a At 12 hpf, angioblasts are located within the anterior and posterior lateral plate mesoderm (LPM) in two bilateral stripes. Presumably, even at…
