Fig. 11.1 Early folliculogenesis . Germ cell cysts break down after birth and primordial follicles form in mouse. In humans, these events occur in utero. Germ cell specific factors considered…
Disorder of primordial follicle endowment X chromosome dysfunction Monosomy (Haploinsufficiency) Trisomy or polysomy X, or mosaic variants Autosomal/X translocations Macrodeletion Xp or Xq Xq (long arm) Basic helix–loop–helix protein (BHLHB9)…
Fig. 1.1 Follicular estrogen production: granulosa cells convert testosterone to estrogen via the aromatase enzyme in the developing secondary follicle Fig. 1.2 Ovarian follicular reserve declines with age, with full…
© Springer International Publishing Switzerland 2016Nanette F. Santoro and Amber R. Cooper (eds.)Primary Ovarian Insufficiency10.1007/978-3-319-22491-6_12 12. Hormone Replacement Therapy in Women with POI: A Patient’s Perspective Christine M. Joachim1 (1) Rachel’s Well, MacLean, VA, USA …
© Springer International Publishing Switzerland 2016Nanette F. Santoro and Amber R. Cooper (eds.)Primary Ovarian Insufficiency10.1007/978-3-319-22491-6_10 10. Primary Ovarian Insufficiency (POI) and Mood Disorders Kris Bevilacqua1 (1) Department of Ob/Gyn and Women’s Health, Albert Einstein College of…
Primary ovarian insufficiency, or POI, affects 1 in 10,000 women by age 20 1 in 1000 by age 30 1 in 100 by age 40 Source: Lawrence Nelson, National Institute…
© Springer International Publishing Switzerland 2016Nanette F. Santoro and Amber R. Cooper (eds.)Primary Ovarian Insufficiency10.1007/978-3-319-22491-6_8 8. IVF and Egg Donation: Special Considerations Deborah E. Ikhena1 and Jared C. Robins2 (1) Division of Reproductive Endocrinology, Northwestern University Feinberg School of…
© Springer International Publishing Switzerland 2016Nanette F. Santoro and Amber R. Cooper (eds.)Primary Ovarian Insufficiency10.1007/978-3-319-22491-6_3 3. Signs and Symptoms of Primary Ovarian Insufficiency Amanda A. Allshouse1, 2 and Amy L. Semple3 (1) Department of Biostatistics and Informatics, Colorado School…
Syndrome Candidate POI genes Location Associated findings Turner syndrome USP9X, ZFX, BMP15 X chromosome Short stature, webbed neck, low-set ears, widely spaced nipples, cardiac anomalies BPES (blepharophimosis-ptosis-epicanthus inversus syndrome) FOXL2…
© Springer International Publishing Switzerland 2016Nanette F. Santoro and Amber R. Cooper (eds.)Primary Ovarian Insufficiency10.1007/978-3-319-22491-6_7 7. Noninvasive Approaches to Enhance Ovarian Function Lisa Marii Cookingham1 and Laxmi A. Kondapalli2 (1) Kaiser Permanente Northern California, 1650 Response Road, 1A, Sacramento,…
