Fig. 3.1 Association of pericytes and endothelial cells. a Schematic representation of endothelial cells (blue) and mural cells (pink). Vascular smooth muscle cells cover larger vessels such as arterioles. In…
Fig. 16.1 Antihypertensive, antithrombotic, and antiatherosclerotic effects of endothelial nitric oxide synthase (eNOS). The eNOS enzyme in endothelial cells (ECs) can be activated by shear stress or agonists such as…
Fig. 4.1 Fibroblast growth factor receptor 1 (FGFR1) signal transduction. The binding of FGF-1, -2, or -4 at the interface of the IgII and IgIII domains, together with the binding…
Fig. 7.1 Extracellular matrix (ECM) ligands and receptors. Both ECM ligands and receptors typically possess modular structure, containing domains that allow them to bind to each other as well as…
Fig. 9.1 Cytochrome P450 (CYP)-dependent metabolism of n-6 (arachidonic and linoleic acid) and n-3 (eicosapentaenoic and docosahexaenoic acid), and metabolism of the epoxides generated to the corresponding diols by the…
Junction stabilization Small GTPase Effectors Molecular function GEF Rap1 a Epac a (cAMP-dependent) PDZ-GEF 1 a (cAMP-independent) C3G b Stabilization of VE-cadherin at junctions Rac Tiam (Rac specific)…
Fig. 5.1 Lymphatic vessel basics. Interstitial fluid and immune cells pass through discontinuous adherens junctions on lymphatic capillaries in a unidirectional manner. One of the main markers for lymphatic capillaries…
Fig. 21.1 Left CC IR at IMF Fig. 21.2 Left CC IMF plus 2 cm Handy Hints In order to achieve maximum breast footprint and optimum compression force balance between…
Fig. 4.1 Cysts. Medio-Lateral Oblique (MLO) view showing multiple ovoid/lobulated lesions (arrow). Parenchymal structures can be seen through the lesion. The low density, ovoid shape and partial halo suggest a…
Fig. 16.1 Integrated direct digital mammography system. 1 X-ray tube, 2 X-ray beam, 3 compression paddle, 4 breast support, 5 detector, 6 C-arm, 7 monitor for angle, breast thickness and…
