Antituberculosis Drugs Alexander O. Tuazon Cecilia C. Maramba-Lazarte Tuberculosis remains a major global health problem, though the incidence per capita, prevalence, and death rates for tuberculosis are falling. Current challenges…
Anthelminthic Drugs in Children David J. Diemert Introduction Worldwide, some of the most common childhood infections are caused by helminths. Of these, schistosomiasis and the soil-transmitted helminths (STHs) which include…
Macrolides, Chloramphenicol, and Tetracyclines Basim I. Asmar Nahed M. Abdel-Haq Macrolides Erythromycin Erythromycin is the prototype of the macrolides. It has been one of the main antibiotics used in the…
Fluoroquinolones Urs B. Schaad Background Despite class label warnings against use in children, prescriptions for quinolone antibiotics to treat infections in children have become increasingly prevalent. Many of the characteristics…
Aminoglycosides and Glycopeptides Matthijs de Hoog John N. van den Anker Aminoglycosides General Aspects of Aminoglycosides Aminoglycosides have played a major role in antimicrobial therapy since their discovery in the…
Penicillins, Cephalosporins, and Other β-Lactams Sumathi Nambiar William J. Rodriguez The Penicillins Introduction Alexander Fleming discovered penicillin in 1928 (1). In the 1940s, penicillin became available for use in clinical…
Sulfonamides Chokechai Rongkavilit Nahed Abdel-Haq Jocelyn Y. Ang Basim I. Asmar Introduction Sulfonamides are some of the most common and the oldest antimicrobial agents used in children. Their mode of…
Ophthalmologic Drugs in Infants and Children John D. Roarty Introduction The study of ocular pharmacology in the pediatric population is often limited to case reports and small clinical series. This…
Topical Medications Victoria Tutag Lehr Mirjana Lulic Botica Merene Mathew Topical administration represents an important method of delivery of medications for infants and children. Clinicians must remember to inquire about…
Drug Therapy in the Adolescent Ian M. Paul Richard L. Levine Adolescence is a novel period in human development in which marked physical and physiologic changes occur. These are compounded…
