Growth Hormone

Sep 7, 2016 by in PEDIATRICS Comments Off on Growth Hormone

Growth Hormone Celia Rodd Harvey J. Guyda Introduction The therapeutic use of growth hormone (GH), derived from human cadaveric pituitaries, was introduced in the late 1950s and early 1960s (1)….

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Thyroid Hormones

Sep 7, 2016 by in PEDIATRICS Comments Off on Thyroid Hormones

Thyroid Hormones Delbert A. Fisher Thyroid hormones are critically important to normal growth and development during infancy, childhood, and adolescence. Thyroid hormone deficiency during fetal life and infancy leads to…

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Insulin and Diabetes Mellitus

Sep 7, 2016 by in PEDIATRICS Comments Off on Insulin and Diabetes Mellitus

Insulin and Diabetes Mellitus Tania S. Burgert Eda Cengiz William Tamborlane Prior to the advent of insulin therapy, the life expectancy of children with type-1 diabetes mellitus (T1DM) was approximately…

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Glucocorticoids

Sep 7, 2016 by in PEDIATRICS Comments Off on Glucocorticoids

Glucocorticoids Evangelia Charmandari Tomoshige Kino George P. Chrousos Introduction Glucocorticoids regulate a broad spectrum of physiologic functions essential for life and play an important role in the maintenance of basal…

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Gastrointestinal Drugs

Sep 7, 2016 by in PEDIATRICS Comments Off on Gastrointestinal Drugs

Gastrointestinal Drugs Catherine O’Brien Jennifer Lowry Kristine Palmer Henry C. Farrar Gregory L. Kearns Laura P. James Introduction Gastrointestinal disorders are common in children and a wide variety of drugs…

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Antihypertensive Agents

Sep 7, 2016 by in PEDIATRICS Comments Off on Antihypertensive Agents

Antihypertensive Agents Thomas G. Wells Mohammad Ilyas Russell W. Chesney Deborah P. Jones Until 1997, few antihypertensive agents were studied systematically in children, and very few were labeled for use…

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Nonsteroidal Anti-Inflammatory Drugs

Sep 7, 2016 by in PEDIATRICS Comments Off on Nonsteroidal Anti-Inflammatory Drugs

Nonsteroidal Anti-Inflammatory Drugs Sylvain Chemtob Véronique G. Dorval Inflammation is among the most important tissue responses to injury; it is observed in all acquired disorders as well as genetic conditions…

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Analgesic Agents

Sep 7, 2016 by in PEDIATRICS Comments Off on Analgesic Agents

Analgesic Agents Sinno H.P. Simons Brian J. Anderson Dick Tibboel Introduction It was generally believed that neonates were unable to experience pain (1). The importance of antinociceptive therapy in children,…

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Immunosuppressive and Immunomodulatory Drugs

Sep 7, 2016 by in PEDIATRICS Comments Off on Immunosuppressive and Immunomodulatory Drugs

Immunosuppressive and Immunomodulatory Drugs Amrish Jain Rudolph P. Valentini Tej K. Mattoo Scott A. Gruber Introduction Organ transplantation has been performed successfully in infants, children, and adolescents for over four…

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