Developmental Abnormalities
Introduction Developmental abnormalities of the skin are a diverse group of anomalies representing errors in morphogenesis. By definition, they are present at birth, although some are not evident in the…
Viral Infections
Introduction Viral infections can induce a remarkable variety of cutaneous manifestations in the neonate and toddler. The clinical manifestations of any viral infection are influenced by the virulence, tissue tropism,…
Eczematous Disorders
Introduction Eczematous eruptions represent a significant proportion of the skin diseases affecting neonates and infants. Clinically they are characterized by erythema, edema, scale, and sometimes crusts. The most common disorder…
Iatrogenic and Traumatic Injuries
Introduction A variety of untoward events may befall the developing infant while in utero or postpartum. Some of these perinatal problems are inherent in the birth process. Others are related…
Bacterial Infections
Introduction Bacterial skin infections in neonates and infants can present differently from those in older children, based on several factors: (1) the nature of the pathogen; (2) the developmental stage…
Inherited and Acquired Blistering Diseases
Inherited blistering diseases Epidermolysis bullosa Epidermolysis bullosa (EB) is a family of rare, inherited disorders characterized by fragility of the skin and sometimes the mucosa in response to minor mechanical…
Lesional Morphology and Assessment
Introduction Newborn infant skin can manifest with an extraordinary array of conditions. Neonatal cutaneous findings may indicate transitory, benign processes such as erythema toxicum neonatorum, or may represent important harbingers…
Diagnostic and Therapeutic Procedures
Introduction Diagnostic and therapeutic procedures are a standard part of the evaluation and management of dermatologic conditions in neonates and infants. Performing procedures on younger children can be technically challenging,…
Fetal Skin Development
Introduction The skin simultaneously contacts a changing environment and provides closure for the body. It is a cellular and molecular interface, which plays a critical functional role in neurobehavior and…
Fetal Skin Development
Introduction The skin simultaneously contacts a changing environment and provides closure for the body. It is a cellular and molecular interface, which plays a critical functional role in neurobehavior and…
