Cytomegalovirus Infections
Cytomegalovirus Infections CMV is the most common congenital viral infection of humans in the United States and is one of the most important opportunistic pathogens causing serious illness and death…
Herpes Simplex Virus Infections
Herpes Simplex Virus Infections Infections caused by herpes simplex virus (HSV) are common in the United States. Conservative estimates had placed the number of people each year that have their…
Introduction
Introduction Microorganisms can reach and infect a fetus or newborn via a number of routes. Vertical spread of a pathogen from an infected mother can occur in utero, during delivery,…
Bacterial and Fungal Infections
Bacterial and Fungal Infections Robert L. Schelonka Bishara J. Freij George H. McCracken Jr. Infections cause significant mortality and long-term morbidity in neonates, especially for premature infants of very low…
Acknowledgments
Acknowledgments The authors are grateful to Dr. Hans Hitzler (Division of Hematology/Oncology, The Hospital for Sick Children, Toronto, Canada); Dr. Eyal Grunebaum (Division of Immunology, The Hospital for Sick Children,…
Thrombosis and Embolism
Thrombosis and Embolism Thromboembolism (TE) is uncommon in the neonatal period. However, TE can cause significant morbidity and mortality. Neonatal TE represents approximately 50% of the TE in the pediatric…
Transfusion of Blood and Blood Products
Transfusion of Blood and Blood Products Transfusions of blood products to newborn infants are essential in many clinical situations, and guidelines for transfusion practice in this patient population have been…
Leukocytes
Leukocytes Neutrophil Disorders A diverse group of leukocyte disorders is encountered in newborn infants. Different blood cells are involved (e.g., neutrophils, lymphocytes, eosinophils), and the disorders may be quantitative or…
