Plasma biomarker discovery in preeclampsia using a novel differential isolation technology for circulating extracellular vesicles

May 10, 2017 by in GYNECOLOGY Comments Off on Plasma biomarker discovery in preeclampsia using a novel differential isolation technology for circulating extracellular vesicles

Objective To circumvent the complex protein milieu of plasma and discover robust predictive biomarkers for preeclampsia (PE), we investigate if phospholipid-binding ligands can reduce the milieu complexity by extracting plasma…

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Noninvasive prenatal screening for fetal trisomies 21, 18, 13 and the common sex chromosome aneuploidies from maternal blood using massively parallel genomic sequencing of DNA

May 10, 2017 by in GYNECOLOGY Comments Off on Noninvasive prenatal screening for fetal trisomies 21, 18, 13 and the common sex chromosome aneuploidies from maternal blood using massively parallel genomic sequencing of DNA

Materials and Methods Clinical methodology This is a prospective multicenter observational study of the application of a laboratory developed test. Women at 31 clinical sites judged by their attending physicians…

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Systematic review and metaanalysis on nonclassic cardiovascular biomarkers after hypertensive pregnancy disorders

May 10, 2017 by in GYNECOLOGY Comments Off on Systematic review and metaanalysis on nonclassic cardiovascular biomarkers after hypertensive pregnancy disorders

Objective The aim of this study was to investigate which nonclassic cardiovascular biomarkers are associated with persistent endothelial dysfunction after pregnancy in women with a history of hypertensive pregnancy disorders…

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