Objective Clear cell carcinoma of the ovary is a distinct subtype of epithelial cancer associated with chemoresistance and poor outcome compared with serous papillary carcinomas. Resistance to paclitaxel has been…
We read with great interest the article by Chervenak et al and are very supportive, corroborating with their arguments and challenges, especially sharing our apprehension of recent statements by professional…
Objective Patients with locally advanced vulvar carcinoma can be treated with primary surgery or neoadjuvant chemoradiation. Neoadjuvant treatment appears to be associated with decreased morbidity and acceptable long-term outcomes. We…
Objective Several conditions are associated with increased preeclampsia (PE) risk. Whether altered maternal angiogenic factor levels contribute to risk in these conditions is unknown. Our objective was to compare angiogenic…
We write this letter in response to the Journal Club Roundtable discussion on our article, “Use of topiramate in pregnancy and risk of oral clefts.” We agree with the noted…
The article below summarizes a roundtable discussion of a study published in this issue of the Journal in light of its methodology, relevance to practice, and implications for future research….
Objective The objective of the study was to assess the outcome of trial of labor after cesarean (TOLAC) in women with past failed operative vaginal delivery (OVD). Study Design A retrospective…
Objective The purpose of this study was to determine risk factors that are associated with hypoxic ischemic encephalopathy (HIE). Study Design This was a case-control study that included newborn infants…
Objective Regret after tubal ligation continues to be a problem. After tubal ligation, couples have the option of tubal surgery or in vitro fertilization (IVF). Study Design Using decision analysis…
Objective Preeclampsia (PE) is associated with hypertension and elevated endothelin (ET-1), an indicator of endothelial cell activation and dysfunction. Reduction of uteroplacental perfusion (RUPP) in the pregnant rat model of…
