Senile-Like Appearance
Progeria Syndrome (Hutchinson-Gilford Syndrome) Early Aging with Alopecia, Atrophy of Subcutaneous Fat, Skeletal Hypoplasia and Dysplasia The following entry was recorded in the St. James Gazette in 1754: “March 19,…
Recognizable Patterns of Malformation
Chromosomal Abnormality Syndromes Identifiable on Routine Karyotype Down Syndrome (Trisomy 21 Syndrome)Hypotonia, Flat Facies, Slanted Palpebral Fissures, Small Ears Down’s report in 1866 on the ethnic classification of idiots stated…
Very Small Stature, Not Skeletal Dysplasia
Cornelia de Lange syndrome (Brachmann–De Lange Syndrome) Synophrys, Thin Downturning Upper Lip, Micromelia The syndrome was originally reported in 1933 by Cornelia de Lange, although Brachmann described a child with…
Deletion, Duplication, and Microduplication Syndromes Identifiable Using Molecular Technology
1p36 Deletion Syndrome (Monosomy 1p36 Deletion Syndrome) Large Anterior Fontanel, Deep-Set Eyes, Pointed Chin First delineated in 1997 as a recognizable pattern of malformation, monosomy 1p36 is the most commonly…
Quantitative and qualitative assessment of an all-inclusive postpartum human papillomavirus vaccination program
Background A postpartum human papillomavirus vaccination program was locally implemented to address low initiation rates among young adults. Within 20 months, the program achieved high vaccine initiation and series completion…
Timing of diagnosis of complex lower urinary tract injury in the 30-day postoperative period following benign hysterectomy
Background Complex lower urinary tract injury resulting from hysterectomy is a rare but highly morbid complication. Although intraoperative recognition reduces the risk of serious sequelae, observational studies have shown that…
Mind-body (hypnotherapy) treatment of women with urgency urinary incontinence: changes in brain attentional networks
Background Prior study of patients with urgency urinary incontinence by functional magnetic resonance imaging showed altered function in areas of the brain associated with interoception and salience and with attention….
Embryo biopsy and perinatal outcomes of singleton pregnancies: an analysis of 16,246 frozen embryo transfer cycles reported in the Society for Assisted Reproductive Technology Clinical Outcomes Reporting System
Background Preimplantation genetic testing is commonly performed by removing cells from the trophectoderm, the outer layer of the blastocyst, which subsequently forms the placenta. Because preimplantation genetic testing removes the…
Pelvic organ prolapse after 3 modes of hysterectomy: long-term follow-up
Background There are various indications and approaches for hysterectomy; yet, the difference in long-term risk of subsequent prolapse after surgery is not well studied. Objective To assess the risk of…
The coronavirus disease 2019 vaccine in pregnancy: risks, benefits, and recommendations
The coronavirus disease 2019 has caused over 2 million deaths worldwide, with over 412,000 deaths reported in Unites States. To date, at least 57,786 pregnant women in the United States…
