A painful reminder
Case notes A 31-year-old nulligravida presented with a 5-day history of new, constant, stabbing pain in the suprapubic region and right lower quadrant of the abdomen. It was not associated…
Abdominal sacrocolpopexy and urinary incontinence: Elser et al
The article below summarizes a roundtable discussion of a study published in this issue of the Journal in light of its methodology, relevance to practice, and implications for future research….
The effect of live and web-based education on the accuracy of blood-loss estimation in simulated obstetric scenarios
Objective Visual estimation of blood loss has been shown to be inaccurate. The objective of this study was to evaluate the impact of a didactic training program on the accuracy…
Prenatal diagnosis and outcome of isolated interrupted inferior vena cava
Objective Report our experience in prenatal diagnosis of 11 cases of interrupted inferior vena cava, summarize the clinical significance and implications of this variant. Study Design Retrospective analysis of 11…
Prenatal intraabdominal bowel dilation is associated with postnatal gastrointestinal complications in fetuses with gastroschisis
Objective The purpose of this study was to determine whether prenatal intraabdominal bowel dilation (IBD) is associated with increased postnatal complications in fetuses with gastroschisis. Study Design A retrospective review…
Transfer of bisphenol A across the human placenta
Objective The objective of the investigation was to study placental transfer and conjugation of bisphenol A (BPA) across the human placenta. Study Design Human placentae obtained from healthy term singleton…
Genomic loss of imprinting in first-trimester human placenta
Objective The purpose of this study was to investigate imprinting patterns in first-trimester human placentas. Study Design Using samples of 17 first-trimester and 14 term placentas from uncomplicated pregnancies, we…
Identification and characterization of proteins in amniotic fluid that are differentially expressed before and after antenatal corticosteroid administration
Objective We sought to examine changes in the intraamniotic proteomic environment after the administration of antenatal corticosteroids to women with impending preterm delivery. Study Design Amniotic fluid samples were collected…
Evidence of a gene-environment interaction that predisposes to spontaneous preterm birth: a role for asymptomatic bacterial vaginosis and DNA variants in genes that control the inflammatory response
Objective We determined whether an environmental exposure to bacterial vaginosis (BV) modified genetic susceptibilities for spontaneous preterm delivery within genes that regulate the inflammatory response. Study Design Maternal DNA samples…
Role of human placental apical membrane transporters in the efflux of glyburide, rosiglitazone, and metformin
Objective Substrates of placental efflux transporters could compete for a single transporter, which could result in an increase in the transfer of each substrate to the fetal circulation. Our aim…
