14: Neonatal outcomes after maternal sepsis: A population-based cohort study




Objectives


Maternal sepsis is associated with high maternal morbidity and mortality. However, neonatal outcomes after maternal sepsis during pregnancy have not been described. The goal of this study was to examine the associations between maternal sepsis and adverse neonatal outcomes.




Methods


This is a retrospective cohort study of all cases of antepartum maternal sepsis at time of delivery in California from 2005-2008 as recorded in the state birth certificate registry that is linked with statewide hospital discharge and death certificate data. Maternal sepsis was identified by ICD-9 codes and to focus on antepartum sepsis, we excluded associated codes of postpartum sepsis, endometritis, wound infection, and mastitis. Fetal anomalies and triplet gestations and higher were also excluded. Comparisons were made between cases of sepsis and all other births without a sepsis code, using chi-squared or Fisher’s exact test, as appropriate. Multivariable logistic regression was performed adjusting for maternal age, parity, race/ethnicity, education, insurance status, degree of prenatal care, gestational age, and twin gestation.




Methods


This is a retrospective cohort study of all cases of antepartum maternal sepsis at time of delivery in California from 2005-2008 as recorded in the state birth certificate registry that is linked with statewide hospital discharge and death certificate data. Maternal sepsis was identified by ICD-9 codes and to focus on antepartum sepsis, we excluded associated codes of postpartum sepsis, endometritis, wound infection, and mastitis. Fetal anomalies and triplet gestations and higher were also excluded. Comparisons were made between cases of sepsis and all other births without a sepsis code, using chi-squared or Fisher’s exact test, as appropriate. Multivariable logistic regression was performed adjusting for maternal age, parity, race/ethnicity, education, insurance status, degree of prenatal care, gestational age, and twin gestation.

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May 2, 2017 | Posted by in GYNECOLOGY | Comments Off on 14: Neonatal outcomes after maternal sepsis: A population-based cohort study

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